Recent Critical Care News

Upvote Story 8
As expected, higher levels of BLS training correlated with better cardiopulmonary resuscitation (CPR) quality. However, this study showed that ventilations and hands-on time were the components of CPR that were most affected by the level of training. Self-assessments of CPR ability correlated well to actual test performance and may have a role in probing CPR skills in students. The results may be important for BLS... Read More | Comment
Upvote Story 12
Early enteral nutrition (EEN), typically started within 48 h after ICU admission, is recommended to be superior over delayed enteral nutrition and parenteral nutrition. The ESICM Working Group on Gastrointestinal Function provided clinical practice guidelines on EEN and suggested to initiate it at a low rate, as beneficial effects regarding infection prevention have been demonstrated in critically ill patients, as well as in patients with... Read More | Comment
Upvote Story 10
Although there are limited studies investigating the safety and efficacy of an intermittent rather than continuous feeding regimen in critically ill adults, there are several theoretical advantages. Further studies should investigate these and in the meantime, feeding regimens should be devised based on individual patient factors. Few studies have investigated the effect of intermittent feeding over continuous feeding. Read More | Comment
Upvote Story 4
We read with great interest the recent letter to Critical Care by Marik and Hooper. Vitamin C is increasingly recognized as a crucial compound to alleviate morbidity in critically ill patients. Vitamin C concentrations, however, are usually far below normal and even close to “scurvy levels” in this population. Vitamin C also is substantially cleared by continuous renal replacement therapy (CRRT). Significant vitamin C deficiency... Read More | Comment
Upvote Story 26
This recently released practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the ICU. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented,... Read More | Comment
Upvote Story 8
Until modifications in chimeric antigen receptor T-cell therapy decrease their toxicities, the intensivist will play a leading role in the management of critically ill chimeric antigen receptor T-cell patients. As this novel immunotherapeutic approach becomes widely available, all critical care clinicians need to be familiar with the recognition and management of complications associated with this treatment. This article is a comprehensive review of the available... Read More | Comment
Upvote Story 5
Resuscitated cardiac arrest is associated with high mortality; however, the ability to estimate risk of adverse outcomes using existing illness severity scores is limited. Using in-hospital data available within the first 24 hours of admission, we aimed to develop more accurate models of risk prediction using both logistic regression (LR) and machine learning (ML) techniques, with a combination of demographic, physiologic, and biochemical information. ML... Read More | Comment
Upvote Story 13
Manual of ICU Procedures is a comprehensive, step-by-step guide to intensive care procedures. The book is divided into four anatomical sections, and a final miscellaneous section. Section one covers airway and respiratory, followed by; vascular and cardiac; neurological; gastrointestinal, abdominal, and genitourinary procedures. Each section covers an extensive range of procedures, and each chapter begins with basic principles before describing the procedure step-by-step. Read More | Comment
Upvote Story 4
Hospital mortality in acute respiratory distress syndrome (ARDS) is approximately 40%, but mortality and trajectory in “mild” acute respiratory distress syndrome (classified only since 2012) are unknown, and many cases are not detected. Approximately 80% of cases of mild acute respiratory distress syndrome persist or worsen in the first week; in all cases, the mortality is substantial (30%) and is higher (37%) in those in... Read More | Comment
Upvote Story 5
Acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. For this reason, automated “sniffer” systems that analyse electronic records have been developed to assist clinicians with ARDS diagnosis. However, a new systematic review found that these sniffer tools had moderate to high predictive value in their derivation cohorts, indicating that published literature had potential for high risks of bias... Read More | Comment
Upvote Story 4
When we talk about triage, we could mean several things. We might mean the triage of patients arriving in the ED to assign clinical priority (because not everyone can be seen instantly); we might mean the triage of patients in a major incident or battlefield scenario; or we could mean the triage of patients to an appropriate level of care within the hospital. (E.g. Critical... Read More | Comment
Upvote Story 5
Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly observed in severe critical illness. We hypothesized that metabolic profiles significantly differ between critically ill patients relative to their level of plasma mtDNA. Differential metabolic profiles during critical illness are associated with cell-free plasma ND1 mtDNA levels that are indicative... Read More | Comment
Upvote Story 14
As with anything in medical field, there are so many resources that it is difficult and time consuming to determine which ones are the most valuable and worth reading. Therefore, we decided to compile a list of the Best Critical Care books any intensivist should consider. Here is a compilation of best sellers and few hidden gems that are trending in the healthcare industry now. Read More | Comment
Upvote Story 7
A short course of intravenous vitamin C in pharmacological dose seems a promising, well tolerated, and cheap adjuvant therapy to modulate the overwhelming oxidative stress in severe sepsis, trauma, and reperfusion after ischemia. Large randomized controlled trials are necessary to provide more evidence before wide-scale implementation can be recommended. Vitamin C is a key circulating antioxidant with anti-inflammatory and immune-supporting effects, and a cofactor for... Read More | Comment
Upvote Story 6
Lower respiratory tract infections (LRTIs) are the leading cause of infectious disease-related deaths worldwide yet remain challenging to diagnose because of limitations in existing microbiologic tests. In critically ill patients, noninfectious respiratory syndromes that resemble LRTIs further complicate diagnosis and confound targeted treatment. This prospective observational study evaluated adults with acute respiratory failure requiring mechanical ventilation who were admitted to the University of California, San... Read More | Comment