New-onset Atrial Fibrillation in the ICU
Patients who develop new-onset atrial fibrillation (NOAF) during an ICU admission are at a higher risk of in-hospital death and readmission to hospital with AF, heart failure, and stroke than those who do not. Using the... read more
Difficulties Faced by Nurses Who Care For Patients with Delirium in the ICU
We developed a difficulty scale for nurses caring for patients with delirium in the intensive care unit and confirmed its reliability and validity. The difficulty factors were developed with the intention to identify educational... read more
Acquired Weakness and Hospital Functional Mobility Outcomes Following Invasive Mechanical Ventilation in Patients with COVID-19
In critically ill COVID-19 patients, the incidence of ICUAW and acute gait dependence were high. Our study identifies factors influencing both outcomes. Future studies should investigate optimal COVID-19 ARDS management and... read more
Medical Nutrition Therapy and Clinical Outcomes in Critically Ill Adults
Calorie intake was mainly provided according to the targets recommended by the active ESPEN guideline, but protein intake was lower. In patients staying in ICU ≥ 5 days, early moderate daily calorie and protein intakes... read more
Sepsis Protocols to Reduce Mortality in Resource-restricted Settings
Simplified sepsis protocols are essential to improving sepsis-related mortality rates in resource-restricted settings, but adequate training of clinicians and modified protocols are necessary for successful implementation. Six... read more
Disposable Hospital Gowns May Pose Infection Risk
Disposable gowns designed to deflect the splatter of bodily fluids, used in thousands of U.S. hospitals, have underperformed in recent and ongoing laboratory tests and may fall short of safety standards, leaving health care... read more
Lower vs. Higher Oxygenation Targets in ICU Patients with Severe Hypoxemia
Among adult ICU patients with severe hypoxemia, a lower oxygenation target (8 kPa) did not improve survival or HRQoL at 1 year as compared to a higher oxygenation target (12 kPa). We obtained 1‑year vital status for... read more
Prevalence of PICS in Mechanically Ventilated Patients with COVID-19
Coronavirus disease 19 (COVID-19) patients usually require long periods of mechanical ventilation and sedation, which added to steroid therapy, favours a predisposition to the development of delirium and subsequent mental... read more
The Mysterious Vanishing of MIS-C
Whilst the overwhelming majority of Covid-19 infections in healthy children are mild or asymptomatic, the serious risk which remained was of the hyperinflammatory syndrome known as MIS-C (Multi-system Inflammatory Syndrome... read more
Management of RV-Predominant Heart Failure and Shock in the Cardiac ICU
Cardiogenic shock from left ventricular failure is a common presentation in the intensive care unit. In contrast, right ventricular (RV)-predominant heart failure (HF) causing shock is less well recognized. We review... read more
Multiple Organ Dysfunction in Older Major Trauma Critical Care Patients
Frailty rather than chronological age appears to drive multiple organ dysfunction syndrome (MODS) development, recovery, and outcome in older cohorts. Early identification of frailty after trauma may help to predict MODS... read more
Arterial Carbon Dioxide and Acute Brain Injury in VA-ECMO
Acute brain injury (ABI) occurs frequently in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). We examined the association between peri-cannulation arterial carbon dioxide tension (PaCO2) and... read more
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Nasal High-Flow Therapy during Neonatal Endotracheal Intubation
Among infants undergoing endotracheal intubation at two Australian tertiary neonatal intensive care units, nasal high-flow therapy during the procedure improved the likelihood of successful intubation on the first attempt... read more