Oxford Textbook of Critical Care

Oxford Textbook of Critical Care

The thoroughly revised 2nd edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely the book takes a problem-orientated approach... read more

Prone vs. Supine Position Ventilation in Intubated COVID-19 Patients

Prone vs. Supine Position Ventilation in Intubated COVID-19 Patients

Whether prone positioning of patients undergoing mechanical ventilation for COVID-19 pneumonia has benefits over supine positioning is not clear. We conducted a systematic review with meta-analysis to determine whether prone... read more

Handbook of Sepsis

Handbook of Sepsis

This recently released practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the ICU. Readers will find information on... read more

The ICU Book

The ICU Book

A fundamental and respected resource book in critical care, The ICU Book, continues to provide the current and practical guidance that have made it the best-selling text in critical care. The text addresses both the medical... read more

Significant Persistent Pain Symptoms After Critical Care Illness

Significant Persistent Pain Symptoms After Critical Care Illness

Persistent pain could be a common health problem after critical illness care. Our data also suggest that there is a lack of specific follow-up after ICU discharge. Given the major consequences on patient quality of life,... read more

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Intubating critically ill patients is a process that requires a well-thought-out, step-by-step plan, specific to each patient. This book teaches the steps necessary to predict, prepare, perform, and provide pre and post-intubation... read more

Cardiovascular Subphenotypes in ARDS

Cardiovascular Subphenotypes in ARDS

Latent class analysis (LCA) of transthoracic echocardiography (TTE) parameters identified four cardiovascular subphenotypes in acute respiratory distress syndrome (ARDS) that more closely aligned with circulatory failure... read more

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Heparin-induced thrombocytopenia (HIT) is a serious iatrogenic complication of heparin treatments. The diagnosis of HIT is difficult in the intensive care setting because thrombocytopenia is a frequent and multifactorial... read more

Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19

Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19

Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity of treatment effect (HTE) across individuals. Better understanding... read more

Family Centered Care At The EOL in the ICU

Family Centered Care At The EOL in the ICU

In the context of end-of-life (EOL) care in the intensive care unit (ICU), recent research has often focussed on patients' families. Studies have shown the importance of communication between ICU clinicians and families,... read more

Predicting Deterioration of Sepsis Patients Using Continuous HVR Analysis

Predicting Deterioration of Sepsis Patients Using Continuous HVR Analysis

We showed that continuous electrocardiograms (ECG) recordings can be automatically analyzed and used to extract heart rate variability (HRV) features associated with clinical deterioration in sepsis. The predictive accuracy... read more

High-risk Pulmonary Embolism in the ICU

High-risk Pulmonary Embolism in the ICU

According to the European guidelines, high-risk pulmonary embolism (PE) is defined as PE associated with hemodynamic instability, including sustained hypotension, cardiogenic shock and/or cardiac arrest. High-risk PE... read more

Positive or Negative Prognostic Factor for Epidural Hematoma?

Positive or Negative Prognostic Factor for Epidural Hematoma?

To our best knowledge, a typical epidural hematoma (EDP) prognosis is good if it is discovered quickly and managed. Therefore the presence of EDH is considered a positive prognostic sign in the Rotterdam, Stockholm, and the... read more

Postextubation Complications vs. Positive-Pressure Suctioning Techniques

Postextubation Complications vs. Positive-Pressure Suctioning Techniques

Currently available studies that compared post-extubation complications in subjects managed with the positive-pressure and suctioning techniques were summarized. Further high-quality studies with a robust study design and... read more