AKI Risk Factors in ICU Patients Using Colistin

AKI Risk Factors in ICU Patients Using Colistin

Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more

Ilofotase Alfa Doesn’t Improved Survival Among Critically Ill Patients with SA-AKI

Ilofotase Alfa Doesn’t Improved Survival Among Critically Ill Patients with SA-AKI

Sepsis-associated acute kidney injury (SA-AKI) in patients admitted to an intensive care unit is associated with significant morbidity and mortality. There is currently no pharmaceutical treatment. Although we found no... read more

A Global Perspective on AKI After Major Surgery

A Global Perspective on AKI After Major Surgery

Acute kidney injury (AKI) is an abrupt decline in kidney function occurring within hours or days. In patients having surgery, postoperative AKI is a major complication associated with adverse outcomes including mortality.... read more

Initiation of CRRT vs. Intermittent Hemodialysis in Critically Ill Patients with Severe AKI

Initiation of CRRT vs. Intermittent Hemodialysis in Critically Ill Patients with Severe AKI

In critically ill patients with severe acute kidney injury (AKI), initiation of continuous renal replacement therapy (CRRT), as compared to intermittent hemodialysis (IHD), was associated with a significant reduction in the... read more

Optimal RRT for Critically Ill Patients with Severe AKI

Optimal RRT for Critically Ill Patients with Severe AKI

In critically ill patients with severe acute kidney injury (AKI), initiation of continuous renal replacement therapy (CRRT), as compared to intermittent hemodialysis (IHD), was associated with a significant reduction in the... read more

Urine Output-based Sepsis-associated AKI: Clinical Implications

Urine Output-based Sepsis-associated AKI: Clinical Implications

This paper offers comprehensive insights into the epidemiology of acute kidney injury (AKI), and we commend the authors for their significant contribution. They revealed an increase in the number of mild cases among AKI stage... read more

Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI)

Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI)

In a comprehensive multinational study, approximately one in five patients develop PO-AKI after major surgery. Increasing severity of PO-AKI is associated with a progressive increase in adverse outcomes. Our findings indicate... read more

AKI Defined by Fluid-Corrected Creatinine in Premature Neonates

AKI Defined by Fluid-Corrected Creatinine in Premature Neonates

In this secondary analysis of the multicenter PENUT trial, we describe fluid-corrected acute kidney injury (AKI) and evaluate associations with short-term and long-term outcomes in premature neonates with fluid-corrected... read more

Blood Purification for Adult Patients with Sepsis

Blood Purification for Adult Patients with Sepsis

Our network meta-analysis (NMA) suggests that plasma exchange and polymyxin-B hemoperfusion may provide potential benefits for adult patients with severe infection or sepsis/septic shock when compared with standard care alone,... read more

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Venous congestion is a pathophysiological state where high venous pressures cause organ edema and dysfunction. Venous congestion is associated with worse outcomes, particularly acute kidney injury (AKI), for critically ill... read more

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

During the COVID-19 pandemic, healthcare delivery was affected in various ways. For example, acute and chronic cardiovascular diseases (CVDs) and events were less frequently observed in hospitals, both because public health... read more

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Remdesivir, an antiviral medication, may benefit patients who are infected with mild or moderate forms of COVID-19 infection. Several research findings have suggested the safety and efficacy of remdesivir for a five- to 10-day... read more

Acute Kidney Injury in ICU Patients

Acute Kidney Injury in ICU Patients

Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains... read more

CEUS Value in Diagnosis of AKI in ICU patients

CEUS Value in Diagnosis of AKI in ICU patients

Ultrasound can assess renal perfusion, but its role in the evaluation of acute kidney injury (AKI) is still unclear. This prospective cohort study was to investigate the value of contrast-enhanced ultrasound (CEUS) in the... read more