Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Science is digging for the varied presentation of COVID-19 patients exposed to the same risk factors, and medical conditions may be influenced by the presence of polymorphic genetic variants. This study investigated the link... read more

Broad Spectrum Vasopressors

Broad Spectrum Vasopressors

We propose the notion of "broad spectrum vasopressors" wherein patients with septic shock are started on multiple vasopressors with a different mechanism of action simultaneously while the vasopressor sensitivity is assessed.... read more

Vasodilatory Shock in the ICU and the Role of Angiotensin II

Vasodilatory Shock in the ICU and the Role of Angiotensin II

With the approval and release of angiotensin II, a new vasoactive agent is now available to utilize in these patients. Overall, the treatment for vasodilatory shock should not be a one-size fits all approach and should be... read more

Angiotensin converting enzyme defects in shock: implications for future therapy

Angiotensin converting enzyme defects in shock: implications for future therapy

Patients who develop vasodilatory shock, particularly when caused by an inflammatory condition like sepsis or pancreatitis, have evidence of significant endothelial injury as manifested by coagulation disorders and increased... read more