Aspirin is Linked with Increased Risk of Heart Failure

Aspirin is Linked with Increased Risk of Heart Failure

Aspirin use is associated with a 26% raised risk of heart failure in people with at least one predisposing factor for the condition. That’s the finding of a study published today in ESC Heart Failure, a journal of the European... read more

Impact of Mobilization on Vital Signs and Oxygen Saturation in Open-Heart Surgery

Impact of Mobilization on Vital Signs and Oxygen Saturation in Open-Heart Surgery

Early and frequent mobilization did not cause vital signs and oxygen saturation to deviate from normal limits in open-heart surgery patients. The difference between pulse and systolic blood pressure values measured before... read more

Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest

Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest

Among patients with in-hospital cardiac arrest, administration of vasopressin and methylprednisolone, compared with placebo, significantly increased the likelihood of return of spontaneous circulation. However, there is uncertainty... read more

Use of Hemoadsorption in Patients With Severe Intoxication Requiring ECMO

Use of Hemoadsorption in Patients With Severe Intoxication Requiring ECMO

Drugs intoxications often lead to severe vasoplegia and cardiogenic shock, and VA-ECMO represents a viable therapy option. However, as cardiopulmonary support is not contributing to the removal of the causal agent from the... read more

Endothelial Glycocalyx Degradation Contributes to Metabolic Acidosis in Children After Cardiopulmonary Bypass Surgery

Endothelial Glycocalyx Degradation Contributes to Metabolic Acidosis in Children After Cardiopulmonary Bypass Surgery

Our data show that metabolic acidosis (increased strong ion gap) is associated with plasma concentration of heparan sulfate, a negatively charged glycosaminoglycan cleaved from the endothelial glycocalyx during cardiopulmonary... read more

The Unsung Heroes: Respiratory Therapists

The Unsung Heroes: Respiratory Therapists

Working day after day, year after year, in a busy high acuity ICU, we all have become a "second family." The public doesn't hear much about respiratory therapists, especially during this COVID nightmare. But they have... read more

Cardiac Injury in COVID-19

Cardiac Injury in COVID-19

Patients with coronavirus disease 2019 (COVID-19) can present with a large panel of cardiac manifestations, including myocardial infarction with (type 1) or without (type 2) obstructive coronary artery disease, arterial or... read more

Diaphragm Dysfunction After Cardiac Surgery

Diaphragm Dysfunction After Cardiac Surgery

Symptomatic diaphragmatic dysfunction was found in 7.6% of patients after cardiac surgery. It led to an increase of respiratory complications, such as pneumonia, prolonged ventilation, and intensive care. Coronary bypass... read more

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest

Low levels of brain injury markers in blood are associated with good neurological outcome after CA. Incorporating biomarkers into neuroprognostication may help prevent premature withdrawal of life-sustaining therapy. Retrospective... read more

A Perspective on Post-Cardiac Arrest Syndrome

A Perspective on Post-Cardiac Arrest Syndrome

This book presents a valuable new perspective on Post-Cardiac Arrest Syndrome (PCAS), which was defined as system failure following whole-body ischemia-reperfusion injuries by the 2008 International Liaison Committee on Resuscitation.... read more

Textbook of Cardiorenal Medicine

Textbook of Cardiorenal Medicine

This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings... read more

Mythbusting: (Empty IVC + Hyperkinetic Heart) Does Not Equal Volume Depletion

Mythbusting: (Empty IVC + Hyperkinetic Heart) Does Not Equal Volume Depletion

An empty IVC and hyperkinetic heart does not equal volume depletion. This combination of echocardiographic findings may result from either vasodilatory shock (as illustrated above) or hypovolemic shock. If encountered in... read more

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

COVID-19 patients with pre-existing coronary artery disease represented a higher abnormal percentage of cardiac markers, accompanied by high mortality and ICU admission rate. BNP together with hs-TNI, α- HBDH, CK-MB and... read more

Sedation with Midazolam After Cardiac Surgery in Children with and without Down Syndrome

Sedation with Midazolam After Cardiac Surgery in Children with and without Down Syndrome

The majority of children with and without Down syndrome required additional sedation after cardiac surgery. This pharmacokinetic and pharmacodynamic analysis does not provide evidence for different dosing of midazolam in... read more