Critical Care: A New Nurse Faces Death, Life, and Everything in Between

Critical Care: A New Nurse Faces Death, Life, and Everything in Between

Doctors heal, or try to, but as nurses we step into the breach, figure out what needs to be done for any given patient today, on this shift, and then, with love and exasperation, do it as best as we can. Critical Care... read more

What to Know About Merkel Cell Carcinoma, the Rare Cancer that Killed Jimmy Buffett

What to Know About Merkel Cell Carcinoma, the Rare Cancer that Killed Jimmy Buffett

"Margaritaville" singer Jimmy Buffett died of Merkel cell carcinoma, a rare but aggressive form of skin cancer, according to a tribute posted on his official websiteopens in a new tab or window. The 76-year-old music icon... read more

Thiamine Deficiency: Pearls and Pitfalls

Thiamine Deficiency: Pearls and Pitfalls

Although thiamine would not be isolated until 1911, the clinical syndrome of thiamine deficiency was recognized as far back as 2700 BC, when the term "beriberi", meaning "wasted wasted" was first coined in China. Nearly 5,000... read more

Characterizing Hydrogels for use in drug delivery systems

Characterizing Hydrogels for use in drug delivery systems

The delivery of drugs to a precise location at the desired concentration without causing toxic effects to the rest of the body has been a challenge to biomedical science for many years. Although several approaches have been... read more

Patient Achieves Remission With CAR-T Cell Therapy for Aggressive Brain Tumors

Patient Achieves Remission With CAR-T Cell Therapy for Aggressive Brain Tumors

A case study published in the December 29 issue of the New England Journal of Medicine outlines the results of a patient treated with his own genetically modified CAR-T cells, using central memory T cells, a stem-cell-like... read more

Frontline PARP inhibitor shrinks tumors in BRCA-positive breast patients

Frontline PARP inhibitor shrinks tumors in BRCA-positive breast patients

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of... read more