Tag: dementia

Upvote Story 13
A New York Times bestseller and international sensation, this stimulating and important book is a fascinating dive into the purpose and power of slumber. Walker is a Professor of Neuroscience and Psychology and the director of the Center for Human Sleep Science at the University of California, Berkeley. Walker spent four years writing the book in which he argues that sleep deprivation is linked to... Read More | Comment
Upvote Story 15
Doctors have gradually come to realize that people who survive a serious brush with death in the intensive care unit are likely to develop potentially serious problems with their memory and thinking processes. This dementia, a side effect of intensive medical care, can be permanent. And it affects as many as half of all people who are rushed to the ICU after a medical emergency.... Read More | Comment
Upvote Story 4
In the primary analysis, limiting the level of sedation provided no significant benefit in reducing incident delirium. However, in a pre-specified subgroup analysis, lighter sedation levels benefitted reducing postoperative delirium for persons with a CCI of 0. Of 200 participants, the mean (SD) age was 82 (8) years, 146 (73%) were women, 194 (97%) were white, and the mean (SD) CCI was 1.5 (1.8). One... Read More | Comment
Upvote Story 8
Mechanical ventilation may be lifesaving, but in certain patient cases it may prolong suffering without a clear benefit. JAMA Internal Medicine published a study of 635,008 hospitalizations of nursing-home patients with advanced dementia and severe functional impairment. Between 2000 and 2013, the use of mechanical ventilation nearly doubled among these patients in some 2,600 cohort hospitals, yet the one-year mortality of ventilated patients remained above... Read More | Comment
Upvote Story 5
Delirium in the presence of the pathologic processes of dementia is associated with accelerated cognitive decline beyond that expected for delirium or the pathologic process itself. These findings suggest that additional unmeasured pathologic processes specifically relate to delirium. Age-related cognitive decline has many contributors, and these findings at the population level support a role for delirium acting independently and multiplicatively to the pathologic processes of... Read More | Comment
Upvote Story 12
Jarem Sawatsky saw the countless guides out there for those caring for the ill and healing the curable, but when he was diagnosed with Huntington’s Disease he found there was nothing for those living with incurable illness. He quit his job as a professor and devoted his life to exploring the possibilities of living with chronic conditions. Now he’s bringing his findings and insights to... Read More | Comment
Upvote Story 5
Every year, about 6 million people are admitted to intensive care units with a life-threatening illness. As medical technology advances, more people survive conditions that once would have been fatal. However, about half of these ICU survivors develop some form of cognitive, psychosocial and physical deficits in a condition known as post-intensive care syndrome, or PICS. Read More | Comment
Upvote Story 18
It remains unclear to what extent postoperative delirium (POD) affects the incidence of dementia in hip fracture patients, and the methods used to detect delirium and dementia require validation. The aim of this study was to investigate the development of dementia within 3 years of femoral neck fracture repair surgery, with a focus on POD as a potential predictive factor. Geriatric hip fracture patients who... Read More | Comment
Upvote Story 15
Delirium (acute confusion) is a serious, common health condition, and it predicts poor outcomes, including greater rates of mortality, institutionalization, prolonged hospitalization, and cognitive impairment. Expedient diagnosis and management are critical to address modifiable delirium causes and improve both quality of care and outcomes. Read More | Comment
Upvote Story 5
Delirium after cardiac surgery commonly, occurs in 25–67 percent of patients. Delirium is a neuropsychiatric syndrome characterized by a change in cognition fluctuates, develops over a short period of time and has an underlying cause. Our findings suggest that older patients with reduced preoperative cognitive functions or who develop postoperative delirium are at risk of developing dementia within 5 years after cardiac surgery. Cognitive functions... Read More | Comment
Upvote Story 4
Hypoactive delirium tends to capture less clinical attention than hyperactive delirium. Like all delirium, it can occur in a variety of patients and settings and will consequently be encountered by many groups of doctors. It can be more difficult to recognize, and is associated with worse outcomes, than hyperactive delirium. This article outlines when to suspect, assess, and appropriately manage patients with hypoactive delirium. Available... Read More | Comment
Upvote Story 4
Objective: To determine the associations between PTSD, psychotropic medication use, and the risk for dementia. PTSD diagnosis significantly increased the risk for dementia diagnosis (HR = 1.35; [95% CI = 1.27–1.43]). However, there were significant interactions between PTSD diagnosis and use of SSRIs (P < .001), NAs (P = .014), and AAs (P < .001) on the risk for dementia diagnosis. HR for dementia diagnosis... Read More | Comment
Upvote Story 8
A new National Institutes of Health (NIH) funded consortium will work to identify and validate trial-ready biomarkers for small vessel diseases in the brain that contribute to cognitive impairment and dementia. Seven participating research sites across the country will develop their own imaging and fluid-based biomarkers and scale them up across the consortium, explained neurologist Steven M. Greenberg, MD, PhD, who will lead the project’s... Read More | Comment