Handbook for Venous Thromboembolism

Handbook for Venous Thromboembolism

A truly practical guidebook for anyone who needs the key information on the diagnosis, management and prevention of venous thromboembolism. Specific areas of focus include understanding the risk factors for VTE and the role... read more

Ground-breaking New AI Technology for Severe Sepsis Rapid Identification

Ground-breaking New AI Technology for Severe Sepsis Rapid Identification

ASEP Medical Holdings Inc. announced the ground-breaking use of artificial intelligence (AI) to rapidly identify infections at increased risk of severe sepsis. The method was developed by the Hancock Lab, under the guidance... read more

Choosing Wisely Interventions to Reduce Antibiotic Overuse

Choosing Wisely Interventions to Reduce Antibiotic Overuse

These real-world multicomponent interventions responding to physician pay-for-performance (P4P) incentives were associated with substantial reductions in antibiotic prescriptions for acute respiratory tract infections (ARTIs)... read more

Comparison of ETA and BALF mNGS in Severe Pneumonia

Comparison of ETA and BALF mNGS in Severe Pneumonia

Our study showed that some differences in the microbiological diagnosis via endotracheal aspirate (ETA) mNGS and bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) appear to exist. Clinicians... read more

Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients

Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients

As common clinical indicators for predicting sepsis, both HBP and D-dimer have high diagnostic effectiveness. Furthermore, the combined application of these two biomarkers can achieve favorable effects. In clinical practice,... read more

Rapid Sepsis Tests Using Magnetic Nanoparticles

Rapid Sepsis Tests Using Magnetic Nanoparticles

Qun Ren, an Empa researcher, and her team are currently developing a diagnostic procedure that can rapidly detect life-threatening blood poisoning caused by staphylococcus bacteria. Staphylococcal sepsis is fatal in up... read more

Deep Learning-based Electrocardiographic Screening for Chronic Kidney Disease

Deep Learning-based Electrocardiographic Screening for Chronic Kidney Disease

Undiagnosed chronic kidney disease (CKD) is a common and usually asymptomatic disorder that causes a high burden of morbidity and early mortality worldwide. We developed a deep learning model for CKD screening from routinely... read more

Traumatic Hemorrhage and Chain of Survival

Traumatic Hemorrhage and Chain of Survival

Trauma is the number one cause of death among Americans between the ages of 1 and 46 years, costing more than $670 billion a year. Following death related to central nervous system injury, hemorrhage accounts for the majority... read more

Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

In this study, the identification of the etiology of shock by Point-of-Care Ultrasound (POCUS) was characterized by high sensitivity and a positive likelihood ratio, especially for obstructive shock. Hence, these findings... read more

Resuscitative TEE

Resuscitative TEE

The use of ED resuscitative transesophageal echocardiography (TEE) is a practical modality that provides useful diagnostic and therapeutic information for critically ill patients in the emergency department, with an excellent... read more

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Heparin-induced thrombocytopenia (HIT) is a serious iatrogenic complication of heparin treatments. The diagnosis of HIT is difficult in the intensive care setting because thrombocytopenia is a frequent and multifactorial... read more

Differential Diagnosis and Cause-specific Treatment During OHCA

Differential Diagnosis and Cause-specific Treatment During OHCA

The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be... read more

Clinical Cases in Critical Care

Clinical Cases in Critical Care

In Clinical Cases in Critical Care, the authors explore core clinical topics and basic sciences in a practical and realistic way, and include comprehensive discussions focusing on critically unwell patients with a variety... read more

ICU Precision Diagnosis with Metagenomic Sequencing

ICU Precision Diagnosis with Metagenomic Sequencing

Despite promising results, metagenomics remains underutilized in the ICU. Several factors still limit its inclusion in routine critical care, including the lack of definitive clinical trials testing its utility, few laboratories... read more