Tag: diagnostics
Bedside Voluntary and Evoked Forces Evaluation in ICU Patients
Around one third of intensive care unit (ICU) patients will develop severe neuromuscular alterations, known as intensive care unit-acquired weakness (ICUAW), during their stay. The diagnosis of ICUAW is difficult and often... read more
Validation of Sputum Gram Stain for Treatment of CAP and HCAP
The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more
Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic
The coronavirus disease (COVID-19) pandemic has challenged healthcare systems and has resulted in complex diagnostic processes for patients with non-COVID-19 pathology. Here, we demonstrate a case of massive alveolar... read more
Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients
Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more
Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression
COVID-19 has evolved into a long-term population health problem that requires new types of diagnostics. Diagnostic developers, therefore, are called on to expand their developmental focus to include novel tests to predict... read more
Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients
Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve.... read more
Barriers to reporting guideline adherence in POCUS research
Although investigators and editors recognise the importance of completely reported research, reporting quality is still a core issue for point-of-care ultrasound (POCUS) research. The shared opinion held by investigators... read more
COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test
Urine foaming test (UFT) is useful, particularly in predicting the clinical severity of COVID-19. The UFT could be recommended as a point of care test, rapid and non-invasive method in the diagnosis and follow-up of COVID-19. A... read more
Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls
A 62-year-old male with a history of hypertension, congestive heart failure, type II diabetes mellitus, and tobacco use presents to the emergency department (ED) with severe left lower leg pain that started six hours ago.... read more
Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine
In this review, we provide an overview of the role of fatty acid-derived lipid mediators as endogenous regulators of the inflammatory, anti-inflammatory and pro-resolving response and future directions for use of clinical... read more
Smell test may help spot COVID-19 cases
A scratch-and-sniff screening tool that identifies impaired sense of smell, a common symptom of COVID-19, could help quickly pinpoint cases. Researchers from the University of Colorado in Boulder studied a smell test called... read more
An Online Tool to Simulate the Effect of Pooled Testing for COVID-19
This diagnostic study describes an online tool created with actual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus copy number data to help policy makers understand how pooled testing compares with single-sample... read more
Cancer Biomarker Measurement using a Smartphone
Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more
Critical Care Medicine: Principles of Diagnosis and Management in the Adult
Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually... read more