Bedside Voluntary and Evoked Forces Evaluation in ICU Patients

Bedside Voluntary and Evoked Forces Evaluation in ICU Patients

Around one third of intensive care unit (ICU) patients will develop severe neuromuscular alterations, known as intensive care unit-acquired weakness (ICUAW), during their stay. The diagnosis of ICUAW is difficult and often... read more

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more

Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic

Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic

The coronavirus disease (COVID-19) pandemic has challenged healthcare systems and has resulted in complex diagnostic processes for patients with non-COVID-19 pathology. Here, we demonstrate a case of massive alveolar... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more

Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression

Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression

COVID-19 has evolved into a long-term population health problem that requires new types of diagnostics. Diagnostic developers, therefore, are called on to expand their developmental focus to include novel tests to predict... read more

Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients

Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients

Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve.... read more

Barriers to reporting guideline adherence in POCUS research

Barriers to reporting guideline adherence in POCUS research

Although investigators and editors recognise the importance of completely reported research, reporting quality is still a core issue for point-of-care ultrasound (POCUS) research. The shared opinion held by investigators... read more

COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test

COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test

Urine foaming test (UFT) is useful, particularly in predicting the clinical severity of COVID-19. The UFT could be recommended as a point of care test, rapid and non-invasive method in the diagnosis and follow-up of COVID-19. A... read more

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

A 62-year-old male with a history of hypertension, congestive heart failure, type II diabetes mellitus, and tobacco use presents to the emergency department (ED) with severe left lower leg pain that started six hours ago.... read more

Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine

Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine

In this review, we provide an overview of the role of fatty acid-derived lipid mediators as endogenous regulators of the inflammatory, anti-inflammatory and pro-resolving response and future directions for use of clinical... read more

Smell test may help spot COVID-19 cases

Smell test may help spot COVID-19 cases

A scratch-and-sniff screening tool that identifies impaired sense of smell, a common symptom of COVID-19, could help quickly pinpoint cases. Researchers from the University of Colorado in Boulder studied a smell test called... read more

An Online Tool to Simulate the Effect of Pooled Testing for COVID-19

An Online Tool to Simulate the Effect of Pooled Testing for COVID-19

This diagnostic study describes an online tool created with actual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus copy number data to help policy makers understand how pooled testing compares with single-sample... read more

Cancer Biomarker Measurement using a Smartphone

Cancer Biomarker Measurement using a Smartphone

Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more

Critical Care Medicine: Principles of Diagnosis and Management in the Adult

Critical Care Medicine: Principles of Diagnosis and Management in the Adult

Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually... read more