Prevalence for Delirium in Stroke Patients

Prevalence for Delirium in Stroke Patients

These results underline the importance of delirium screening in stroke patients specifically during the night. Since even short delirious episodes are associated with more complications and increased disability, future studies... read more

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe TBI

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe TBI

Among patients with severe traumatic brain injury (TBI), early prophylactic hypothermia compared with normothermia did not improve neurologic outcomes at 6 months. These findings do not support the use of early prophylactic... read more

Co-Occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness

Co-Occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness

In this multicenter cohort study, one or more post-intensive care syndrome problems were present in the majority of survivors, but co-occurring problems were present in only one out of four. Education was protective from... read more

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

In adults with out-of-hospital cardiac arrest, the use of epinephrine resulted in a significantly higher rate of 30-day survival than the use of placebo, but there was no significant between-group difference in the rate of... read more

The burdens of survivorship: an approach to thinking about long-term outcomes after critical illness

The burdens of survivorship: an approach to thinking about long-term outcomes after critical illness

Internationally accepted approaches to the study of functioning and disability can inform critical care practitioners and scholars in their study of functional limitations, disability, and quality of life after critical illness... read more

The Association of Frailty with Post-ICU Disability, Nursing Home Admission, and Mortality

The Association of Frailty with Post-ICU Disability, Nursing Home Admission, and Mortality

Pre-ICU frailty status was associated with increased post-ICU disability and new nursing home admission among ICU survivors, and death among all admissions. Pre-ICU frailty status may provide prognostic information about... read more

The Prognostic Value of MRI in Moderate and Severe TBI

The Prognostic Value of MRI in Moderate and Severe TBI

Traumatic brain injury (TBI) is a major cause of death and disability, yet many predictors of outcome are not precise enough to guide initial clinical decision-making. Although increasingly used in the early phase following... read more

Critical Illness, Disability, and the Road Home

Critical Illness, Disability, and the Road Home

Ability to participate in the community is an important outcome for all patients after a major illness, it signposts reaching the end of the road home. A patient's ability to return to the priority tasks of daily living impacts... read more

Frailty and Subsequent Disability and Mortality among Patients with Critical Illness

Frailty and Subsequent Disability and Mortality among Patients with Critical Illness

The prevalence of frailty (diminished physiologic reserve) and its effect on outcomes for those aged 18 years and older with critical illness is unclear. Frailty is common in critically ill adults aged 18 years and older... read more

Smoking, vitamin D deficiency linked to early MS disability

Smoking, vitamin D deficiency linked to early MS disability

Severe vitamin D deficiency and current smoking predicted accumulated disability in patients with clinically isolated syndrome, which can be a precursor to the development of multiple sclerosis.... read more