Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly observed in severe... read more

The Case for CRISPR-Cas9

The Case for CRISPR-Cas9

Few techniques in the history of modern science have made as large an impact in as short a time as CRISPR-Cas9. Only a few years after the technique was first described, its inventors are predicted to be on the shortlist... read more

Memory of a heart attack is stored in our genes

Memory of a heart attack is stored in our genes

Both heredity and environmental factors influence our risk of cardiovascular disease. A new study shows now that the memory of a heart attack can be stored in our genes through epigenetic changes.... read more