Troponins for SVT Set the Stage for Patient Harm

Troponins for SVT Set the Stage for Patient Harm

Many laboratory tests are routinely ordered for reassurance. We almost always order a hemoglobin and pregnancy test when a patient has syncope, despite knowing the vast majority will be normal. These tests are accurate... read more

Transfusion Strategies for Acute Upper Gastrointestinal Bleeding

Transfusion Strategies for Acute Upper Gastrointestinal Bleeding

As compared with a liberal transfusion strategy, a restrictive strategy significantly improved outcomes in patients with acute upper gastrointestinal bleeding. We enrolled 921 patients with severe acute upper gastrointestinal... read more

Relative Hypoglycemia in Diabetic Patients With Critical Illness

Relative Hypoglycemia in Diabetic Patients With Critical Illness

In ICU patients with diabetes, relative hypoglycemia is common, increases with higher hemoglobin A1C levels, and is a modifiable risk factor for both mortality and subsequent absolute hypoglycemia. These findings provide... read more

Is Hemoglobin Good for Cerebral Oxygenation and Clinical Outcome in Acute Brain Injury?

Is Hemoglobin Good for Cerebral Oxygenation and Clinical Outcome in Acute Brain Injury?

Hemoglobin is important for cerebral oxygenation and strategies to minimize anemia should be undertaken. higher hemoglobin levels are associated with less cerebral ischemia and better clinical outcome, whether this remains... read more

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Transfusion of red blood cells is an everyday practice in critical care with the primary aim of restoring adequate tissue oxygenation. However, blood transfusion may also be harmful and costly, therefore a so called restrictive... read more

Incident Diabetes in Survivors of Critical Illness and Mechanisms Underlying Persistent Glucose Intolerance

Incident Diabetes in Survivors of Critical Illness and Mechanisms Underlying Persistent Glucose Intolerance

Diabetes and pre-diabetes occur frequently in survivors of ICU experiencing stress hyperglycemia. Based on the occurrence rate observed in this cohort, structured screening and intervention programs appear warranted. Consent... read more

Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold

Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold

Long-term mortality rates and HRQoL did not differ in patients with septic shock and anaemia who were transfused at a haemoglobin threshold of 7 g/dl versus a threshold of 9 g/dl. We may reject a more than 3 % increased hazard... read more

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Haemoglobin concentration decreases during resuscitation from septic shock, and has a significant but weak association with the volume of intravenous fluids administered. Median (IQR) haemoglobin concentration at baseline... read more