Acute Kidney Injury in ICU Patients

Acute Kidney Injury in ICU Patients

Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains... read more

Antiviral Drug Discovery and Development

Antiviral Drug Discovery and Development

This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced... read more

Long-Term Opioid Prescription Linked to Higher Risk of Hepatitis C

Long-Term Opioid Prescription Linked to Higher Risk of Hepatitis C

Exposure to long-term prescription opioid therapy was linked to a three times higher risk of HCV seroconversion compared to individuals who were prescription opioid-naïve or acute. Prescription opioid use is associated... read more

Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure

Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure

N-acetylcysteine (NAC) is well known to emergency medicine physicians as the antidote in acute acetaminophen ingestion. The scope of use for this medication beyond that is often not considered, such as in other etiologies... read more

Acute Liver Failure: Evidence-Based Evaluation and Management

Acute Liver Failure: Evidence-Based Evaluation and Management

Although acute liver failure (ALF) is a rare clinical presentation in the ED, it carries a high mortality, morbidity, and resource cost. Across the developing world, the underlying etiology is primarily viral, with hepatitis... read more

Growing Concerns of Hepatitis E in Europe

Growing Concerns of Hepatitis E in Europe

Cases of Hepatitis E in Europe have increased by 10x over 10 years, with 5617 cases in 2015. Testing, case definitions, diagnosis, and surveillance for HEV infection vary extensively across Europe, with only 20 member states... read more

Prominent clinical guidelines fall short of conflict of interest standards

Prominent clinical guidelines fall short of conflict of interest standards

Two recent clinical practice guidelines, one for cholesterol management and another for treatment of chronic hepatitis C, did not meet the Institute of Medicine's standards for limiting commercial conflicts of interest, according... read more

Hepatitis B Drug Combination Approved

Hepatitis B Drug Combination Approved

Tenofovir-alafenamide combination approved by the FDA for chronic hepatitis B infection.... read more

Metabolic syndrome predicts cardiovascular events in HBV infection

Metabolic syndrome predicts cardiovascular events in HBV infection

Metabolic syndrome was associated with a fourfold rise in cardiovascular events among patients with chronic hepatitis B virus infection, according to a prospective cohort study.... read more

FDA Warns About Hepatitis B Reactivation from Hepatitis C Antivirals

FDA Warns About Hepatitis B Reactivation from Hepatitis C Antivirals

The FDA issued a warning yesterday about the risk of hepatitis B virus becoming active again in patients with current or previous infection who received treatment with hepatitis C virus treatments.... read more

Use of interventions improves patient care for viral hepatitis

Researchers recommend multiple, inexpensive interventions be included in screening, diagnosis and treatment programs for patients with hepatitis B and C viruses, in an effort to optimize the outcomes of hepatitis care.... read more