Is Cardiopulmonary Resuscitation Futile in COVID-19 Patients Experiencing In-Hospital Cardiac Arrest?

Is Cardiopulmonary Resuscitation Futile in COVID-19 Patients Experiencing In-Hospital Cardiac Arrest?

COVID-19 patients suffering from in-hospital cardiac arrest had 100% in-hospital mortality regardless of the baseline comorbidities, presenting illness severity, and location of arrest. Out of 1,094 patients hospitalized... read more

Pulmonary Hypertension: ED Presentation, Evaluation, and Management

Pulmonary Hypertension: ED Presentation, Evaluation, and Management

Pulmonary hypertension (PH), characterized by increased pulmonary vascular resistance and pulmonary arterial pressure, is associated with significant morbidity and mortality. The disease is heterogenous, with varying demographics... read more

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

A 62-year-old male with a history of hypertension, congestive heart failure, type II diabetes mellitus, and tobacco use presents to the emergency department (ED) with severe left lower leg pain that started six hours ago.... read more

Increasing suction pressure during endotracheal suctioning increases the volume of suctioned secretions

Increasing suction pressure during endotracheal suctioning increases the volume of suctioned secretions

It may be assumed that 250 mmHg suction pressure, via compliance with open system suction method related procedures, is being more effective and equally safe for secretion cleaning in comparison to the 80 and 150 mmHg suction... read more

Fishman’s Pulmonary Diseases and Disorders

Fishman’s Pulmonary Diseases and Disorders

Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with... read more

Failing to Learn and Learning to Fail

Failing to Learn and Learning to Fail

Last week saw the publication of yet another damning report shining a spotlight on the culture of cover up and denial in our healthcare system. Bill Kirkup’s report—”The Life and Death of Elizabeth Dixon: A Catalyst... read more

Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN

Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN

Dual therapy using sildenafil and milrinone was superior to monotherapy with either drug in neonates with severe persistent pulmonary hypertension (PPHN) and is recommended for use in resource-constrained settings. A double-blind... read more

A Concise Overview of Non-invasive IAP Measurement Techniques

A Concise Overview of Non-invasive IAP Measurement Techniques

This review presents an overview of previously reported non-invasive intra-abdominal pressure (IAP) measurement techniques. Each section covers the basic physical principles and methodology of the various measurement techniques,... read more

Unfractionated Heparin (UFH), LMWH, Fondaparinux, Argatroban, and Bivalirudin

Unfractionated Heparin (UFH), LMWH, Fondaparinux, Argatroban, and Bivalirudin

Unfractionated heparin (UFH) binds to anti-thrombin III (AT-III), which enhances antithrombin's inhibition of several coagulation factors – especially factor Xa and factor IIa (thrombin). Low Molecular-Weight Heparin... read more

VExUS Ultrasound Score – Fluid Overload and Venous Congestion Assessment

VExUS Ultrasound Score – Fluid Overload and Venous Congestion Assessment

Proper fluid management while avoiding fluid overload can be one of the most difficult parts of practicing medicine. Unfortunately, many physicians using ultrasound mainly rely on Inferior Vena Cava (IVC) measurements to... read more

How I Manage Drainage Insufficiency on ECMO

How I Manage Drainage Insufficiency on ECMO

As the use of extracorporeal membrane oxygenation (ECMO) expands, a systematic approach to the management of complex technical issues, such as drainage insufficiency, is essential to improving patient outcomes. Due to... read more

Pretreating Transfused Erythrocytes with NO Prevents Pulmonary Hypertension

Pretreating Transfused Erythrocytes with NO Prevents Pulmonary Hypertension

Researchers at Massachusetts General Hospital (MGH; Boston, USA), Harvard Medical School (HMS; Boston, MA, USA), and other institutions conducted a trial to see if treating stored packed sheep RBCs with NO before transfusion... read more

Human-to-Human Transmission of a Novel Coronavirus in Vietnam

Human-to-Human Transmission of a Novel Coronavirus in Vietnam

This article describe transmission of Coronavirus from a father, who had flown with his wife from Wuhan to Hanoi, to his son. The findings suggest that the incubation period in the son may have been 3 days or less. On... read more

The Neurohormonal Basis of Pulmonary Hypertension in HFpEF

The Neurohormonal Basis of Pulmonary Hypertension in HFpEF

Subjects with heart failure with preserved ejection fraction (HFpEF) display activation of the endothelin and adrenomedullin neurohormonal pathways, the magnitude of which is associated with pulmonary hemodynamic derangements,... read more