De Novo Renal Failure and Clinical Outcomes of Patients With Critical COVID-19

De Novo Renal Failure and Clinical Outcomes of Patients With Critical COVID-19

This case series concludes that respiratory failure conveys significant mortality risk in patients with coronavirus disease 2019 and that survival with concomitant renal failure is rare. This is a case series of patients... read more

COVID-19 Pneumonia: Typical or Atypical Form of ARDS?

COVID-19 Pneumonia: Typical or Atypical Form of ARDS?

Evidence-based guidelines can never help a doctor resolve whether a patient is best managed by inserting an endotracheal tube or avoiding its use. That decision is based on clinical judgment, gestalt, and tacit knowledge.... read more

Delirium Prevalence and Risk Factors for Critically Ill COVID-19 Patients

Delirium Prevalence and Risk Factors for Critically Ill COVID-19 Patients

Acute brain dysfunction was highly prevalent and prolonged in critically ill patients with COVID-19. Benzodiazepine use and lack of family visitation were identified as modifiable risk factors for delirium, and thus these... read more

Estimate Artery Occlusion Pressure in Critically Ill Patients Under Mechanical Ventilation Using Doppler Echocardiography

Estimate Artery Occlusion Pressure in Critically Ill Patients Under Mechanical Ventilation Using Doppler Echocardiography

In mechanically ventilated critically ill patients, Doppler transthoracic echocardiography indices are highly specific but not sensitive to estimate pulmonary artery occlusion pressure. Transmitral early velocity wave... read more

Time-Controlled Adaptive Ventilation Versus Volume-Controlled Ventilation in Experimental Pneumonia

Time-Controlled Adaptive Ventilation Versus Volume-Controlled Ventilation in Experimental Pneumonia

In the model of pneumonia used herein, at the same tidal volume and mean airway pressure, time-controlled adaptive ventilation, compared with volume-controlled ventilation, was associated with less lung damage and bacteremia... read more

The Ventilator Book

The Ventilator Book

If you need something that teaches you both the concepts of mechanical ventilation and how to manage patients with respiratory failure, this is the book for you. The Ventilator Book is written to be read in the ICU or Emergency... read more

Outcomes Associated with the Use of Renin-Angiotensin-Aldosterone System Blockade in Hospitalized Patients with COVID-19 Infection

Outcomes Associated with the Use of Renin-Angiotensin-Aldosterone System Blockade in Hospitalized Patients with COVID-19 Infection

Use of ACEI or ARBs prior to hospitalization was not associated with adverse outcomes in COVID-19 and the therapeutic benefits of continuing ACEI or ARB in hospitalized patients with COVID-19 was not offset by adverse outcomes. Data... read more

Doppler Echocardiographic Indices in Critically Ill Patients Under Mechanical Ventilation

Doppler Echocardiographic Indices in Critically Ill Patients Under Mechanical Ventilation

Doppler Echocardiographic Indices Are Specific But Not Sensitive to Predict Pulmonary Artery Occlusion Pressure in Critically Ill Patients Under Mechanical Ventilation. The objective of this study was to prospectively... read more

Weaning the patient: between protocols and physiology

Weaning the patient: between protocols and physiology

Ventilator weaning forms an integral part in critical care medicine and strategies to shorten duration are rapidly evolving alongside our knowledge of the relevant physiological processes. The purpose of the current review... read more

Clinical characteristics of critically ill patients with COVID-19

Clinical characteristics of critically ill patients with COVID-19

In this study of critical patients infected by SARS-CoV-2 in a high-complexity hospital, the majority were comorbid elderly men, a large percentage required invasive mechanical ventilation, and ICU mortality was 25%. Design... read more

Development and assessment of the performance of a shared ventilatory system

Development and assessment of the performance of a shared ventilatory system

Using standard clinical components, a system of shared ventilation consisting of two ventilatory limbs was assembled and connected to a single ventilator. Individual monitors for each circuit were developed using widely available... read more

What’s new about pulmonary hyperinflation in mechanically ventilated critical patients

What’s new about pulmonary hyperinflation in mechanically ventilated critical patients

Pulmonary hyperinflation is the increase in the relaxation volume of the respiratory system at the end of a tidal expiration (end-expiratory volume). This can occur due to a number of factors, acting alone or in combination,... read more

Mechanical Ventilators for Non-invasive Ventilation

Mechanical Ventilators for Non-invasive Ventilation

This book analyzes and describes the whole spectrum of technical elements related with non-invasive mechanical ventilators technologies, ventilator modes and complementary technologies for correct interpretation and clinical... read more

Airway closure, more harmful than atelectasis in intensive care?

Airway closure, more harmful than atelectasis in intensive care?

Since the mid-1980s, atelectasis has been demonstrated during anesthesia in lung healthy subjects and in intensive care patients suffering from acute respiratory failure and requiring ventilator support. In the latter... read more