No Reason to Choose Tramadol over Morphine

No Reason to Choose Tramadol over Morphine

Tramadol is an opioid, but it does not bind directly to opioid receptors (or it binds so weakly that it might as well not bind at all). Its opioid action is the result of the metabolite O-desmethyltramadol, which means... read more

Doctors Raise Alarm About Shortages Of Pain Medications

Doctors Raise Alarm About Shortages Of Pain Medications

In an informal survey of nearly 2,500 anesthesiologists conducted by the American Society of Anesthesiologists, 98 percent of respondents said they "regularly experience drug shortages at their institutions." More than 95... read more

Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome

Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome

Current pharmacologic treatment of the neonatal abstinence syndrome with morphine is associated with a lengthy duration of therapy and hospitalization. Buprenorphine may be more effective than morphine for this indication.... read more

Clonidine Added to Single-Shot Interscalene Block Confers No Analgesic Benefit

Clonidine Added to Single-Shot Interscalene Block Confers No Analgesic Benefit

A large, retrospective study from Mayo Clinic has concluded that the addition of clonidine to a single-shot interscalene block does not improve the quality of analgesia in patients undergoing total shoulder arthroplasty.... read more