New Study for Opioid Use Patterns

New Study for Opioid Use Patterns

The purpose of this study is to as certain and describe the trajectories of pain experienced by a diverse group of opioid naive patients who are prescribed an opioid analgesic for acute pain. Using a digital health-based... read more

Assessing Movement-Evoked Pain

Assessing Movement-Evoked Pain

One of the most common and nuanced tasks that nurses perform is pain assessment, particularly in acute postoperative settings where frequent reassessments are needed. Most assessments are limited to obtaining a pain intensity... read more

Midazolam and Ketamine Produce Neural Changes in Memory and Pain

Midazolam and Ketamine Produce Neural Changes in Memory and Pain

Painful stimulation during light sedation with midazolam, but not ketamine, can be accompanied by increased coherence in brain connectivity, even though details are less likely to be recollected as explicit memories. In... read more

Study Finds Lower Dose of Ketamine Equally Effective in Reducing Pain

Study Finds Lower Dose of Ketamine Equally Effective in Reducing Pain

Ketamine is known to provide pain relief comparable to opioid medications, which are highly addictive. In the recent study, appearing in the journal Academic Emergency Medicine, researchers studied 98 patients, ages 18 to... read more

Substituting Acetaminophen for Fentanyl Feasible in PCI for STEMI

Substituting Acetaminophen for Fentanyl Feasible in PCI for STEMI

In patients with STEMI given crushed ticagrelor before PCI, using IV acetaminophen instead of IV fentanyl as a painkiller did not increase pain levels or platelet reactivity and prevented delay of ticagrelor's effects, researchers... read more

No Reason to Choose Tramadol over Morphine

No Reason to Choose Tramadol over Morphine

Tramadol is an opioid, but it does not bind directly to opioid receptors (or it binds so weakly that it might as well not bind at all). Its opioid action is the result of the metabolite O-desmethyltramadol, which means... read more

Subanesthetic Ketamine Infusions for the Management of Pediatric Pain in Non‐critical Care Settings

Subanesthetic Ketamine Infusions for the Management of Pediatric Pain in Non‐critical Care Settings

Ketamine can effectively be used as part of a multimodal analgesic regimen in pediatric patients in non‐critical care settings. Our five‐year experience using low‐dose ketamine infusions highlights an acceptable side... read more

Health Canada Eyes Opioid Restrictions for Popular Painkiller

Health Canada Eyes Opioid Restrictions for Popular Painkiller

Health Canada has launched a review of the increasingly popular pharmaceutical drug tramadol – a move that could prompt the department to reverse its controversial, decade-old decision not to classify the medication as... read more

Non-addictive Painkiller Shows Promise in Animal Trials

Non-addictive Painkiller Shows Promise in Animal Trials

Preliminary research in monkeys suggests that a new medication might be able to provide pain relief similar to opioid drugs such as OxyContin, but without the same potential for addiction or serious side effects.... read more