AHRQ Errors Report was “Outright Unconscionable”

AHRQ Errors Report was “Outright Unconscionable”

Headlines this winter screamed the bad news: Emergency physicians are literally killing people! "As many as 250,000 people die every year because they are misdiagnosed in the emergency room, with doctors failing to identify... read more

Postextubation Complications vs. Positive-Pressure Suctioning Techniques

Postextubation Complications vs. Positive-Pressure Suctioning Techniques

Currently available studies that compared post-extubation complications in subjects managed with the positive-pressure and suctioning techniques were summarized. Further high-quality studies with a robust study design and... read more

Regular Old Pneumonia Treatment Just Got Better

Regular Old Pneumonia Treatment Just Got Better

In 2020, COVID-19 pneumonia became so common that "old-fashioned" bacterial pneumonia suddenly seemed rare. They look very different on x-ray. See if you can spot the differences. A new study from France tipped the scales... read more

Hydrocortisone in Severe Community-Acquired Pneumonia

Hydrocortisone in Severe Community-Acquired Pneumonia

Among patients with severe community-acquired pneumonia being treated in the ICU, those who received hydrocortisone had a lower risk of death by day 28 than those who received placebo. A total of 800 patients had undergone... read more

Effect of ICU Quality Control Indicators on VAP Incidence Rate and Mortality

Effect of ICU Quality Control Indicators on VAP Incidence Rate and Mortality

This study highlights the association between the ICU quality control (QC) factors and ventilator-associated pneumonia (VAP) incidence rate and mortality. The process factors rather than the structural factors need to be... read more

Emergence of Ventilator Associated Pneumonia in Critical Care Units

Emergence of Ventilator Associated Pneumonia in Critical Care Units

In intensive care unit, the care of critically ill patients is a primary component of modern medicine. Intensive care units create potential for recovery in patients who otherwise may not have survived. They are, however,... read more

Continuous Positive Airway Pressure Usage During COVID-19

Continuous Positive Airway Pressure Usage During COVID-19

We confirm that use of early continuous positive airway pressure (CPAP) with high-flow output combined with an "ad hoc" algorithm to inform the decision to intubate is a valid and safe strategy for respiratory support in... read more

Postoperative Pulmonary Complications in the ENIGMA II Trial

Postoperative Pulmonary Complications in the ENIGMA II Trial

Respiratory complications remain among the most common and serious adverse outcomes of major surgery. In the Australian and New Zealand Audit of Surgical Mortality, postoperative pneumonia accounted for 44% of infective... read more

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more

Bougie vs. Endotracheal Tube with Stylet on Successful Intubation

Bougie vs. Endotracheal Tube with Stylet on Successful Intubation

Among critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful intubation on the first attempt compared with use of an endotracheal tube with stylet. Among... read more

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside.... read more

Lower vs. Higher Oxygenation Targets in ICU Patients with Severe Hypoxemia

Lower vs. Higher Oxygenation Targets in ICU Patients with Severe Hypoxemia

Among adult ICU patients with severe hypoxemia, a lower oxygenation target (8 kPa) did not improve survival or HRQoL at 1 year as compared to a higher oxygenation target (12 kPa). We obtained 1‑year vital status for... read more

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19

Among critically ill patients with COVID-19, treatment with an antiplatelet agent, compared with no antiplatelet agent, had a low likelihood of providing improvement in the number of organ support–free days within 21 days. The... read more

Pleural Resident Macrophages and Pleural IRA B Cells Promote Immunity Against Pneumonia

Pleural Resident Macrophages and Pleural IRA B Cells Promote Immunity Against Pneumonia

Airway infection is a major cause of mortality worldwide. The identification of new mechanisms aiding in effective host immune response is therefore required. Here, we show that the specific depletion of the pleural immune... read more