Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics

Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing... read more

Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention

Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention

As the pace of research related to COVID-19 continues at an unprecedented rate, clinicians on the front line of the pandemic are challenged to keep up with a deluge of information to ensure they are bringing best practices... read more

Where There Is No Doctor: A Village Health Care Handbook

Where There Is No Doctor: A Village Health Care Handbook

This updated reprint features updated medication information, a newly revised family planning chapter, new treatments for a variety of infections, and more. All Hesperian books are regularly updated and reprinted to reflect... read more

The Hospitalist Role in Treating Opioid Use Disorder

The Hospitalist Role in Treating Opioid Use Disorder

Opioid use disorder, like many of the other conditions we see, is a chronic relapsing remitting medical disease and a risk factor for premature mortality. When a patient with diabetes is admitted with cellulitis, we might... read more

Sepsis Around the Cradle of Humankind

Sepsis Around the Cradle of Humankind

While representing the cutting edge of civilization everywhere, mothers and their newborn infants are a population particularly vulnerable to sepsis.1 By recognizing the importance of antiseptic prophylaxis (handwashing),... read more

Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile

Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile

The hospital environment is a source of pathogen transmission. The effect of enhanced disinfection strategies on the hospital-wide incidence of infection has not been investigated in a multicentre, randomised controlled trial.... read more

Prevention of Low Cardiac Output Syndrome After Pediatric Cardiac Surgery

Prevention of Low Cardiac Output Syndrome After Pediatric Cardiac Surgery

Dobutamine and milrinone are safe, well tolerated, and equally effective in prevention of low cardiac output syndrome after pediatric cardiac surgery. The hemodynamic response of the two drugs is comparable. In uncomplicated... read more

The long sepsis journey in low- and middle-income countries begins with a first step… but on which road?

The long sepsis journey in low- and middle-income countries begins with a first step… but on which road?

Infection and sepsis are among the most frequent acute medical conditions worldwide and result in approximately eight million premature deaths each year, most of which occur in low and lower-middle income countries (LMICs).... read more

The Relationship between Clinical Experience and Quality of Health Care

The Relationship between Clinical Experience and Quality of Health Care

Physicians with more experience are generally believed to have accumulated knowledge and skills during years in practice and therefore to deliver high-quality care. However, evidence suggests that there is an inverse relationship... read more

Prevention of Hospital Infections by Intervention and Training (PROHIBIT)

Prevention of Hospital Infections by Intervention and Training (PROHIBIT)

Results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections. This study demonstrates that multimodal prevention strategies aiming at improving CVC insertion... read more

The Role of Hospital Pharmacist in the Screening, Prevention and Treatment of Delirium

The Role of Hospital Pharmacist in the Screening, Prevention and Treatment of Delirium

An interdisciplinary approach is fundamental for effective prevention and treatment of delirium. Pharmacists could play a role in identifying and resolving medication-related delirium. However, little is known about their... read more

Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients

Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients

Intraoperative infusion of dexmedetomidine for prevention of postoperative delirium and cognitive dysfunction in elderly patients undergoing major elective non-cardiac surgery. Postoperative delirium occurs in 10% to 60%... read more

Diagnosis, Prevention, and Treatment of C. difficile: Current State of the Evidence

Diagnosis, Prevention, and Treatment of C. difficile: Current State of the Evidence

This is a summary of a systematic review that evaluated the recent evidence regarding the accuracy of diagnostic tests and the effectiveness of interventions for preventing and treating Clostridium difficile (C. difficile)... read more

Infection Prevention and Healthcare Associated Infections

Infection Prevention and Healthcare Associated Infections

It is difficult to overstate the importance of healthcare associated infections (HAI). Approximately 4% of patients who enter hospitals in the United States develop an infection related to their hospital care. Although... read more