Serum Protein Changes in Pediatric Sepsis Patients Identified with an Aptamer-Based Multiplexed Proteomic Approach

Serum Protein Changes in Pediatric Sepsis Patients Identified with an Aptamer-Based Multiplexed Proteomic Approach

The serum protein changes identified with the aptamer-based multiplexed proteomics approach used in this study can be useful to distinguish between sepsis and noninfectious systemic inflammation. A cohort of 40 children... read more

A supplemental intravenous amino acid infusion sustains a positive protein balance for 24 hours in critically ill patients

A supplemental intravenous amino acid infusion sustains a positive protein balance for 24 hours in critically ill patients

Providing supplemental amino acids to ICU patients during a 3-h period results in improved whole-body net protein balance, without an increase in amino acid oxidation. The primary objective was to investigate if a 24-h intravenous... read more

Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes. Inflammasomes are... read more