Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors

Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors

This qualitative, multicenter, international study of caregivers of critical illness survivors identified consistently unmet needs, means by which caregivers accessed support post ICU, and several care mechanisms identified... read more

Multicomponent Sepsis Transition Effect and Recovery Program After Sepsis

Multicomponent Sepsis Transition Effect and Recovery Program After Sepsis

In a multisite randomized clinical trial of patients hospitalized with sepsis, patients provided with a 30-day program using a nurse navigator to provide best practices for postsepsis care experienced a lower proportion of... read more

ARDS vs. PseudoARDS – Failure of the Berlin Definition

ARDS vs. PseudoARDS – Failure of the Berlin Definition

True ARDS might be defined as a histological diagnosis involving diffuse alveolar damage throughout the lungs (characterized by hyaline membrane formation and thickening of the alveolar walls). PseudoARDS refers to patients... read more

Changes in Barriers to Implementing Early Mobilization in the ICU

Changes in Barriers to Implementing Early Mobilization in the ICU

This study was undertaken to investigate the rate of mobilization, defined as a rehabilitation level of sitting on the edge of a bed or higher, and its association with changes in barriers in the intensive care unit (ICU).... read more

Inhaled Budesonide Improves Time to COVID-19 Recovery

Inhaled Budesonide Improves Time to COVID-19 Recovery

Inhaled budesonide improves time to recovery, with a chance of also reducing hospital admissions or deaths (although our results did not meet the superiority threshold), in people with COVID-19 in the community who are at... read more

Should We Prolong the Observation Period for Neurological Recovery After Cardiac Arrest?

Should We Prolong the Observation Period for Neurological Recovery After Cardiac Arrest?

Up to 9.6% of cardiac arrest patients with favorable outcomes recover consciousness after the recommended 7 days of observation, indicating the observation time of 7 days seems justified but longer duration may be needed.... read more

RRT in Critically Ill Patients with AKI

RRT in Critically Ill Patients with AKI

Recent evidence has shown that pre-emptive or earlier renal-replacement therapy (RRT) in patients with severe acute kidney injury (AKI) and no urgent indications does not confer clinical benefit. By default, this would imply... read more

Bodily Pain in Survivors of ARDS

Bodily Pain in Survivors of ARDS

Nearly half of acute respiratory distress syndrome (ARDS) survivors reported bodily pain at 6- and 12-month follow-up; one-third reported pain at both time points. Pre-ARDS unemployment, smoking history, and in-ICU opioid... read more

Effect of Neuromuscular Electrical Stimulation on the Recovery of COVID-19 Patients

Effect of Neuromuscular Electrical Stimulation on the Recovery of COVID-19 Patients

The rehabilitation of patients with COVID-19 after prolonged treatment in the intensive care unit is often complex and challenging. Patients may develop a myriad of long-term multiorgan impairments, affecting the respiratory,... read more

Discharged IMV COVID-19 Survivors Not Functionally Independent

Discharged IMV COVID-19 Survivors Not Functionally Independent

The majority of invasive mechanical ventilation (IMV) COVID-19 survivors were not functionally independent at discharge and required significant follow-up medical care. The COVID-19 circumstance has placed constraints on... read more

Confirming a Pulse during Resuscitation

Confirming a Pulse during Resuscitation

Much has been written about using ultrasound in cardiac arrest. The REASON study found that identification of cardiac standstill in PEA or asystole is correlated with almost no chance of meaningful recovery and can assist... read more

Could Physical Therapy Interventions Be Adopted in the Management of Critically Ill Patients with COVID-19?

Could Physical Therapy Interventions Be Adopted in the Management of Critically Ill Patients with COVID-19?

As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this disease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients... read more

NeuroRx Announced Completion of Data Analysis for COVID-19 Treatment Respiratory Failure

NeuroRx Announced Completion of Data Analysis for COVID-19 Treatment Respiratory Failure

NeuroRx, Inc. announced completion of top line data analysis of the 60-day results in its phase 2b/3 clinical trial, conducted under FDA Fast Track Designation, of ZYESAMIâ„¢ (aviptadil acetate) for the treatment of critically-ill... read more

Apremilast Not Likely to Reduce Time to Recovery or Mortality in Critically Ill Patients in I-SPY COVID-19 Trial

Apremilast Not Likely to Reduce Time to Recovery or Mortality in Critically Ill Patients in I-SPY COVID-19 Trial

Quantum Leap Healthcare Collaborative (QLHC), the sponsor of the I-SPY COVID Trial, announced that apremilast (Otezla), made by Amgen, has been dropped for futility. Apremilast was chosen for testing in the I-SPY COVID Trial... read more