Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.... read more

Diabetes Risks and Outcomes in COPD Patients

Diabetes Risks and Outcomes in COPD Patients

The relationship between chronic obstructive pulmonary disease (COPD) and diabetes remains incompletely understood. This study evaluated diabetes risk and post-diabetes outcomes in COPD patients with and without exacerbations.... read more

Critical Illness, Disability, and the Road Home

Critical Illness, Disability, and the Road Home

Ability to participate in the community is an important outcome for all patients after a major illness, it signposts reaching the end of the road home. A patient's ability to return to the priority tasks of daily living impacts... read more

Effect of Procalcitonin-guided Antibiotic Treatment on Mortality in Acute Respiratory Infections

Effect of Procalcitonin-guided Antibiotic Treatment on Mortality in Acute Respiratory Infections

Use of procalcitonin to guide antibiotic treatment in patients with acute respiratory infections reduces antibiotic exposure and side-effects, and improves survival. Widespread implementation of procalcitonin protocols in... read more

Effect of Azithromycin on Asthma Exacerbations and Quality of Life in Adults with Persistent Uncontrolled Asthma

Effect of Azithromycin on Asthma Exacerbations and Quality of Life in Adults with Persistent Uncontrolled Asthma

Adults with persistent symptomatic asthma experience fewer asthma exacerbations and improved quality of life when treated with oral azithromycin for 48 weeks. Azithromycin might be a useful add-on therapy in persistent asthma.... read more

Algorithm Can Diagnose Pneumonia Better than Radiologists

Algorithm Can Diagnose Pneumonia Better than Radiologists

Stanford researchers have developed a deep learning algorithm that evaluates chest X-rays for signs of disease. In just over a month of development, their algorithm outperformed expert radiologists at diagnosing pneumonia.... read more

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine

Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury (AKI) and associated adverse outcomes after angiography without definitive evidence of their efficacy. Among patients at... read more

Predicting outcomes after trauma to the brain

Predicting outcomes after trauma to the brain

UMMS researchers help develop novel tool to predict survival after penetrating brain injury. Using the new tool they developed, the SPIN-Score (Surviving Penetrating Injury to the Brain), two factors were by far the strongest... read more

Perspectives of Survivors, Families and Researchers on Key Outcomes for Research in ARF

Perspectives of Survivors, Families and Researchers on Key Outcomes for Research in ARF

There is heterogeneity among the outcomes evaluated in studies of survivors of acute respiratory failure (ARF). Patient, family and researcher groups supported inclusion of outcome domains that fit within the PICS framework.... read more

Core Outcome Measures for Clinical Research in ARF Survivors

Core Outcome Measures for Clinical Research in ARF Survivors

This Core Outcome Measurement Set is recommended for use in all clinical research evaluating acute respiratory failure (ARF) survivors after hospital discharge. In the future, researchers should evaluate measures for outcomes... read more

Calcium induces chronic lung infections

Calcium induces chronic lung infections

Researchers have now discovered that calcium induces the switch from acute to chronic infection. One of the most serious pathogens is the bacterium Pseudomonas aeruginosa, which frequently causes hospital infections and is... read more

Catheter ablation lowers long-term risk of recurrent stroke in atrial fibrillation patients

Catheter ablation lowers long-term risk of recurrent stroke in atrial fibrillation patients

Atrial fibrillation patients with a prior history of stroke who undergo catheter ablation to treat the abnormal heart rhythm lower their long-term risk of a recurrent stroke by 50 percent. The Intermountain study compared... read more

Endobronchial Ultrasound Can ID Pulmonary Thromboembolism

Endobronchial Ultrasound Can ID Pulmonary Thromboembolism

The researchers found that in four cases (0.7 percent), filling defects were demonstrated in central pulmonary arteries while sampling mediastinal lymph nodes.... read more

Alarm Fatigue in ICU Addressed in Two Studies

Alarm Fatigue in ICU Addressed in Two Studies

Alarm fatigue within the intensive care unit (ICU) can negatively impact patient safety and lead to life-threatening events. Researchers from Harlem Hospital and Maimonides Medical Center aimed to identify solutions fight... read more