Clinical Trial Testing Vitamin and Steroid Combination in Sepsis Patients Underway at Emory

Clinical Trial Testing Vitamin and Steroid Combination in Sepsis Patients Underway at Emory

A new clinical trial at Emory University and 45 other sites around the U.S. will test a combination of vitamins and steroids in patients diagnosed with sepsis. Sepsis is caused by the body's overwhelming and life-threatening... read more

Last Year, The Flu Put Him In A Coma. This Year He’s Getting The Shot

Last Year, The Flu Put Him In A Coma. This Year He’s Getting The Shot

Charlie Hinderliter wasn't opposed to the flu shot. He didn't have a problem with vaccinations. He was one of about 53 percent of Americans who just don't get one. An estimated 80,000 Americans died of the flu, or flu-related... read more

ESPEN Guideline on Clinical Nutrition in the ICU

ESPEN Guideline on Clinical Nutrition in the ICU

Following the new ESPEN Standard Operating Procedures, the previous guidelines to provide best medical nutritional therapy to critically ill patients have been updated. These guidelines define who are the patients at risk,... read more

Early PREdiction of Sepsis Using Leukocyte Surface Biomarkers

Early PREdiction of Sepsis Using Leukocyte Surface Biomarkers

From a large panel of leukocyte biomarkers, immunosuppression biomarkers were associated with subsequent sepsis in ED patients with suspected acute infection. Between January 2014 and February 2016, we recruited 272, 59 and... read more

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

The use of steroids in critically ill patients continues to be controversial. Whilst there are signals for improved cardiovascular parameters, this did not translate to clear mortality benefits. The most recent of these trials... read more

Viral Sepsis in Children

Sepsis in children is typically presumed to be bacterial in origin until proven otherwise, but frequently bacterial cultures ultimately return negative. Although the incidence of viral-induced sepsis is not precisely known,... read more

Circulating Biomarkers May be Unable to Detect Infection at the Early Phase of Sepsis in ICU Patients

Circulating Biomarkers May be Unable to Detect Infection at the Early Phase of Sepsis in ICU Patients

During the study period, 363 patients with SIRS were screened, 84 having exclusion criteria. Ninety‑one patients were classified as having non‑septic SIRS and 188 as having sepsis. Eight biomarkers had an area under... read more

Intensive Care Medicine in 2050: Vasopressors in Sepsis

Intensive Care Medicine in 2050: Vasopressors in Sepsis

Vasopressors are used in sepsis when hypotension is assumed to be mainly due to a decreased arterial tone. However, the appropriate time to initiate vasopressors is not clearly defined, and fluid administration is most... read more

New World Sepsis Day Infographics

New World Sepsis Day Infographics

The new World Sepsis Day Infographics are now available for download, just in time for World Sepsis Day this Thursday. Please download them and feel free to use them as you see fit, on your social media channels, printed... read more

Sepsis: Learn the Signs and Document

Sepsis: Learn the Signs and Document

Writing in the MJA, researchers have reported the findings of a prospective cohort study comparing estimates of the incidence and mortality of sepsis using clinical diagnosis or the Australian and New Zealand Intensive Care... read more

New York State Sepsis Reporting Mandate Appears to Improve Care and Reduce Deaths

New York State Sepsis Reporting Mandate Appears to Improve Care and Reduce Deaths

A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes of death in those who... read more

Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality

Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality

Margaret Parker, MD, MCCM, speaks with Stefanie G. Ames, MD, about the article "Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality," published in the May 2018 issue of Pediatric Critical Care Medicine. Dr. Ames... read more

Rapid Diagnosis of MRSA

Rapid Diagnosis of MRSA

Current standard laboratory methods for detection of oxacillin resistance require for isolation, identification, and susceptibility testing at least 48–72 h, although the multiplex PCR assay used is a rapid, sensitive,... read more

Sepsis Around the Cradle of Humankind

Sepsis Around the Cradle of Humankind

While representing the cutting edge of civilization everywhere, mothers and their newborn infants are a population particularly vulnerable to sepsis.1 By recognizing the importance of antiseptic prophylaxis (handwashing),... read more