Acute Undifferentiated Fever with Thrombocytopenia: Clinical and Etiological Profile

Acute Undifferentiated Fever with Thrombocytopenia: Clinical and Etiological Profile

Prompt recognition and management of thrombocytopenia in acute undifferentiated fever are vital. Thrombocytopenia, along with organ dysfunction and shock, significantly influence patient outcomes. Tailored interventions based... read more

Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

In this study, the identification of the etiology of shock by Point-of-Care Ultrasound (POCUS) was characterized by high sensitivity and a positive likelihood ratio, especially for obstructive shock. Hence, these findings... read more

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Compared with standard calorie and protein targets, early calorie and protein restriction did not decrease mortality but was associated with faster recovery and fewer complications. Of 3,044 patients randomly assigned... read more

Clarifying the Fictions Surrounding Sepsis: Strategies for Improved Management and Outcomes

Clarifying the Fictions Surrounding Sepsis: Strategies for Improved Management and Outcomes

It is important to clarify the myths surrounding sepsis and to provide a clear understanding of the condition. This can help set realistic expectations about outcomes and inform effective strategies for managing sepsis, including... read more

Acid-Base Disorders in the Critically III Patient

Acid-Base Disorders in the Critically III Patient

Acid-base disorders are common in the intensive care unit. By utilizing a systematic approach to their diagnosis, it is easy to identify both simple and mixed disturbances. These disorders are divided into four major categories:... read more

Science and Practice of Pediatric Critical Care Medicine

Science and Practice of Pediatric Critical Care Medicine

The field of critical care medicine is in the midst of a dramatic change. Technological and scientific advances during the last decade have resulted in a fundamental change in the way we view disease processes, such as sepsis,... read more

Vasopressor Choice and Timing in Vasodilatory Shock

Vasopressor Choice and Timing in Vasodilatory Shock

Vasodilatory shock is the most common form of circulatory shock encountered in patients admitted to the intensive care unit (ICU). Sepsis is the predominant etiology, but other causes of vasodilatory shock include postoperative... read more

Essentials of Shock Management: A Scenario-Based Approach

Essentials of Shock Management: A Scenario-Based Approach

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of... read more

Resuscitation with Blood Products in Patients with Trauma-related Hemorrhagic Shock Receiving Prehospital Care

Resuscitation with Blood Products in Patients with Trauma-related Hemorrhagic Shock Receiving Prehospital Care

The trial did not show that prehospital PRBC–LyoPlas resuscitation was superior to 0·9% sodium chloride for adult patients with trauma related hemorrhagic shock. Further research is required to identify the characteristics... read more

Equipotent Ratios for the Most Common Vasopressors

Equipotent Ratios for the Most Common Vasopressors

Calculating equipotent doses between vasopressor agents is necessary in clinical practice and research pertaining to the management of shock. This scoping review summarizes conversion ratios between vasopressors and provides... read more

Intubation Practice and Outcomes Among Pediatric Emergency Departments

Intubation Practice and Outcomes Among Pediatric Emergency Departments

While tracheal intubation (TI) characteristics vary between pediatric Emergency Departments and ICUs, outcomes are similar. Shock and limited mouth opening were independently associated with adverse TI events in the Emergency... read more

Accuracy of Cumulative Volumes of Fluid Challenge in Critically Ill Patients

Accuracy of Cumulative Volumes of Fluid Challenge in Critically Ill Patients

A volume of fluid challenge (FC) of 250 ml with a threshold of 9.6% increase in stroke volume (SV) showed the highest accuracy in detecting fluid responsiveness in critically ill patients with shock. A prospective observational... read more

Predict Sepsis-Associated Vasopressor Use in the ICU

Predict Sepsis-Associated Vasopressor Use in the ICU

Domain adaptation improved performance of a model predicting sepsis-associated vasopressor use during external validation. 40 retrospectively collected features from the electronic medical records of adult ICU patients... read more

Cardiac Injury in COVID-19

Cardiac Injury in COVID-19

Patients with coronavirus disease 2019 (COVID-19) can present with a large panel of cardiac manifestations, including myocardial infarction with (type 1) or without (type 2) obstructive coronary artery disease, arterial or... read more