Provider Burnout and Fatigue During the COVID-19 Pandemic

Provider Burnout and Fatigue During the COVID-19 Pandemic

The novel Coronavirus Disease 2019 (COVID-19) pandemic has resulted in an overall surge in new cases of depression and anxiety and an exacerbation of existing mental health issues, with a particular emotional and physical... read more

Addressing Anxiety Among Health Care Professionals During COVID-19

Addressing Anxiety Among Health Care Professionals During COVID-19

The coronavirus disease (COVID-19) pandemic has become one of the central health crises of a generation. The pandemic has affected people of all nations, continents, races, and socioeconomic groups. The responses required,... read more

US Betrays Healthcare Workers in Coronavirus Disaster

US Betrays Healthcare Workers in Coronavirus Disaster

The handling of the COVID-19 pandemic in the United States will go down as the worst public health disaster in the history of the country. The loss of lives will make 9/11 and so many other catastrophes appear much smaller... read more

COVID-19: A Message From Concerned Physicians

COVID-19: A Message From Concerned Physicians

The COVID-19 pandemic has reached a point where containment is no longer possible. The COVID-19 threat is real, and rapidly getting worse. Many of you are very nervous, some are unsure of the validity of the information you... read more

Moral Distress in the Health Professions

Moral Distress in the Health Professions

This is the first book on the market or within academia dedicated solely to moral distress among health professionals. It aims to bring conceptual clarity about moral distress and distinguish it from related concepts. Explicit... read more

Survivorship Will Be the Defining Challenge of Critical Care in the 21st Century

Survivorship Will Be the Defining Challenge of Critical Care in the 21st Century

Distracted by the high mortality rate of critical illness, we tend to overlook the essential fact that most patients survive the intensive care unit (ICU). Every year, millions of patients are discharged from the ICU... read more

Could Stress Ulcer Prophylaxis Increase Mortality in High-acuity Patients?

Could Stress Ulcer Prophylaxis Increase Mortality in High-acuity Patients?

Although considerable uncertainty remains, the inferences from SUP-ICU and PEPTIC are consistent with the hypothesis that proton pump inhibitors (PPIs) increase the risk of death in patients with higher illness severity.... read more

Which Component of Mechanical Power is Most Important in Causing VILI?

Repeated applications of tidal energy inflict lung damage (VILI) when stress and strain exceed the limits of tissue tolerance. Inflation work and energy are the products of pressure and volume, which are loosely associated... read more

Relative Hyperglycemia Predicts In-Hospital Mortality in Critically Ill Patients

Relative Hyperglycemia Predicts In-Hospital Mortality in Critically Ill Patients

Unlike absolute hyperglycemia, relative hyperglycemia, as assessed by the stress hyperglycemia ratio, independently predicts in-hospital mortality in critically ill patients across the glycemic spectrum. Future studies should... read more

Soluble Urokinase Receptor and AKI

Soluble Urokinase Receptor and AKI

The authors concluded that high suPAR levels were associated with Acute Kidney Injury (AKI) in various clinical and experimental contexts. This cohort study reports that suPAR was associated with subsequent AKI in several... read more

Effects of a Multimodal Program Including Simulation on Job Strain Among Nurses Working in ICUs

Effects of a Multimodal Program Including Simulation on Job Strain Among Nurses Working in ICUs

Among ICU nurses, an intervention that included education, role-play, and debriefing resulted in a lower prevalence of job strain at 6 months compared with nurses who did not undergo this program. Further research is... read more

PPIs vs. Histamine-2 Receptor Blockers for ICU Stress Ulcer Prophylaxis

PPIs vs. Histamine-2 Receptor Blockers for ICU Stress Ulcer Prophylaxis

ICU patients assigned to proton-pump inhibitors (PPIs) versus histamine-2 receptor blockers (H2RBs) for ulcer prophylaxis had marginally higher 90-day mortality that just missed statistical significance. Significantly fewer... read more

Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation

Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation

Among ICU patients requiring mechanical ventilation, a strategy of stress ulcer prophylaxis with use of proton pump inhibitors vs histamine-2 receptor blockers resulted in hospital mortality rates of 18.3% vs 17.5%, respectively,... read more

Could the Furosemide Stress Test Clarify Resuscitative Goals?

Could the Furosemide Stress Test Clarify Resuscitative Goals?

Imagine that you admit a patient with septic shock. You resuscitate the patient as best you can with inopressors, fluids, and antibiotics. An adequate blood pressure is achieved. A reasonable amount of fluid is administered.... read more