Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Despite advances in medical therapies and coronary revascularization, infarct-related cardiogenic shock remains a life-threatening emergency with high death rates. Temporary mechanical circulatory support, including peripheral... read more

ECLS in Infarct-Related Cardiogenic Shock

ECLS in Infarct-Related Cardiogenic Shock

In patients with acute myocardial infarction complicated by cardiogenic shock with planned early revascularization, the risk of death from any cause at the 30-day follow-up was not lower among the patients who received ECLS... read more

Atrial Fibrillation and Ischemic Stroke Patients While on Oral Anticoagulation

Atrial Fibrillation and Ischemic Stroke Patients While on Oral Anticoagulation

Patients with Atrial Fibrillation (AF) and ischemic stroke while on oral anticoagulation are at increased risk of recurrent ischemic stroke and death. These patients currently have an unmet medical need. Individual participant... read more

Acute Ischemic Stroke: Recent Advances in Reperfusion Treatment

Acute Ischemic Stroke: Recent Advances in Reperfusion Treatment

Stroke is a major clinical challenge. The authors note that during the last 5–7 years, tremendous progress was achieved in the reperfusion treatment of acute ischemic stroke during its first few hours from symptom onset.... read more

AHRQ Errors Report was “Outright Unconscionable”

AHRQ Errors Report was “Outright Unconscionable”

Headlines this winter screamed the bad news: Emergency physicians are literally killing people! "As many as 250,000 people die every year because they are misdiagnosed in the emergency room, with doctors failing to identify... read more

Clinical Cases in Critical Care

Clinical Cases in Critical Care

In Clinical Cases in Critical Care, the authors explore core clinical topics and basic sciences in a practical and realistic way, and include comprehensive discussions focusing on critically unwell patients with a variety... read more

Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke

Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke

Ischemic strokes in younger adults, those 18 to 50 years old, account for approximately 10% to 15% of all ischemic strokes. Risk factors for stroke between younger and older patients tend to be similar. Younger patients... read more

Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke

Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke

Between Dec 10, 2019, and Jan 25, 2022, 1,600 patients were enrolled and randomly assigned to tenecteplase (n=816) or alteplase (n=784), of whom 1577 were included in the intention-to-treat (ITT) population (n=806 tenecteplase;... read more

Standardized Data Collection in Prehospital Critical Care

Standardized Data Collection in Prehospital Critical Care

The medical problems categorized by HEMS personnel can be seen as valid. The greatest challenges remain in the classification of stroke and other neurological emergencies. Patients treated by HEMS personnel are characterized... read more

General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke

General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke

The functional outcomes 3 months after endovascular treatment for stroke were similar with general anesthesia and sedation. Our results, therefore, suggest that clinicians can use either approach. Of 351 randomized patients,... read more

Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events in Adults

Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events in Adults

Adult sepsis survivors experience an increased hazard of major cardiovascular events compared to survivors of a non-sepsis hospitalization. 254,241 adult sepsis survivors were matched to adult survivors of non-sepsis hospitalization... read more

Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients

Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients

In patients with arterial hypotension norepinephrine increased end-systolic ventricular elastance and arterial elastance. The effects of norepinephrine on stroke volume depend on baseline ventriculo-arterial coupling. Although... read more

Hemodynamic Status During Endovascular Stroke Treatment

Hemodynamic Status During Endovascular Stroke Treatment

In our protocol-based setting, intraprocedural pre-recanalization BP reductions during endovascular therapy were not associated with functional outcome. However, higher intraprocedural pre-recanalization SBP and MAP were... read more

Adult Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events

Adult Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events

Adult sepsis survivors experience an increased hazard of major cardiovascular events compared to survivors of a non-sepsis hospitalization. 254,241 adult sepsis survivors were matched to adult survivors of non-sepsis hospitalization... read more