High Rate of PICS Among SICU Survivors

High Rate of PICS Among SICU Survivors

Through the successful implementation of a multidisciplinary critical care outpatient clinic (CCOC), this study identifies an exorbitant rate of postintensive care syndrome (PICS) among surgical intensive care unit (SICU)... read more

Baricitinib in COVID-19 Patients

Baricitinib in COVID-19 Patients

In patients hospitalized with COVID-19, baricitinib significantly reduced the risk of death but the size of benefit was somewhat smaller than that suggested by previous trials. The total randomized evidence to date suggests... read more

Developing a Decision Instrument to Guide Abdominal-pelvic Imaging of Blunt Trauma Patients

Developing a Decision Instrument to Guide Abdominal-pelvic Imaging of Blunt Trauma Patients

Although computed tomography (CT) of the abdomen and pelvis (A/P) can provide crucial information for managing blunt trauma patients, liberal and indiscriminant imaging is expensive, can delay critical interventions, and... read more

Bleeding and Thrombotic Events in Patients with Severe COVID‑19 on ECMO

Bleeding and Thrombotic Events in Patients with Severe COVID‑19 on ECMO

In a nationwide cohort of COVID‑19 patients supported by extracorporeal membrane oxygenation (ECMO), bleeding incidence was high and associated with mortality. Intracranial hemorrhage incidence was higher than reported... read more

Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease

Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease

Nasotracheal intubation (NTI) is feasible and safe in neonatal cardiac surgery. System-level engagement with stakeholders is necessary to change clinical practice. NTI facilitates early SLP evaluation and treatment and significantly... read more

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Host biomarker signatures may be able to identify postoperative infection or sepsis up to three days in advance of clinical recognition. If validated in future studies, these signatures offer potential diagnostic utility... read more

Evaluation of an Advanced Critical Care Echocardiography Program

Evaluation of an Advanced Critical Care Echocardiography Program

Trainees perceived lack of time and limited access to supervision as major barriers to course completion. Nevertheless, successful portfolio completion was related to factors other than protected time in the echocardiography... read more

CRT-targeted Fluid Resuscitation vs. Lactate-targeted in Septic Shock

CRT-targeted Fluid Resuscitation vs. Lactate-targeted in Septic Shock

Capillary refill time (CRT)-targeted fluid resuscitation in septic shock was not superior to a lactate-targeted one on early fluid administration or fluid balances. However, it was associated with comparable effects on regional... read more

Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients

Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients

In this large, multicenter database study, early extubation rates in postoperative cardiac patients did not significantly change between 2009 and 2018. Centers that performed early extubation more frequently did not have... read more

MECA in Medical Emergency Situations Significantly Reduced Failure Rates

MECA in Medical Emergency Situations Significantly Reduced Failure Rates

In our simulation, the use of medical emergency cognitive aid (MECA) in medical emergency situations significantly reduced failure rates. The use of MECA was widely accepted, and MECA were easy to use. In a high percentage,... read more

Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke

Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke

Between Dec 10, 2019, and Jan 25, 2022, 1,600 patients were enrolled and randomly assigned to tenecteplase (n=816) or alteplase (n=784), of whom 1577 were included in the intention-to-treat (ITT) population (n=806 tenecteplase;... read more

Temporal Trends and Hospital Variation in Time-to-Antibiotics Among Veterans Hospitalized with Sepsis

Temporal Trends and Hospital Variation in Time-to-Antibiotics Among Veterans Hospitalized with Sepsis

This cohort study across nationwide VA hospitals found that time-to-antibiotics for sepsis has declined over time. However, there remains significant variability in time-to-antibiotics not explained by patient characteristics,... read more

A Decade of Progress in Critical Care Echocardiography

A Decade of Progress in Critical Care Echocardiography

Critical care echocardiography (CCE) is now widely accepted by the critical care community as a valuable tool in the ICU and emergency department, and in perioperative settings. It allows rapid and accurate diagnosis,... read more

New Study for Opioid Use Patterns

New Study for Opioid Use Patterns

The purpose of this study is to as certain and describe the trajectories of pain experienced by a diverse group of opioid naive patients who are prescribed an opioid analgesic for acute pain. Using a digital health-based... read more