Tag: study

Upvote Story 7
Alarm fatigue within the intensive care unit (ICU) can negatively impact patient safety and lead to life-threatening events. Researchers from Harlem Hospital and Maimonides Medical Center aimed to identify solutions fight such fatigue. The first study from New York’s Harlem Hospital, published in Chest. The second study, conducted at Brooklyn’s Maimonides Medical Center and also published in Chest. Read More | Comment
Upvote Story 5
Critical care chest radiography with a portable wireless direct radiography (DRw) system can provide similar or superior information compared to a computed radiography (CR) system regarding clinically significant findings and position of tubes and lines. Most radiologists found significantly fewer artifacts on DRw images compared to CR images and all readers agreed that when present, these artifacts did not significantly preclude the ability to evaluate... Read More | Comment
Upvote Story 6
Ischemic and diffuse neuroaxonal injury to the brain in experimental sepsis, human postmortem brains, and in vivo MRI suggest these two distinct lesion types to be relevant. Future studies should be focused on body fluid biomarkers to detect and monitor brain injury in sepsis. The relationship of neurofilament levels with time from sepsis onset may be of prognostic value. In postmortem rat and human brain... Read More | Comment
Upvote Story 9
Many barriers exist to prevent effective assessment and management of delirium, but several of these are due to a lack of understanding or unfamiliarity with the condition and the assessment tools as well as lack of medical prioritisation of the results. Further research is needed on this topic. Few studies have investigated barriers to delirium assessment and management, but several themes reoccur throughout the literature.... Read More | Comment
Upvote Story 12
Children with complicated pneumonia should be discharged from the hospital with oral instead of intravenous (IV) antibiotics when possible, according to a new study. The results showed no significant differences in treatment failure rates between PICC and oral antibiotics. Conversely, children discharged with PICCs experienced a higher rate of infections, adverse drug reactions, and hospital readmissions, with PICC complications occurring in 7.1% of children who... Read More | Comment
Upvote Story 16
Lung deposition was lower than 20% of nominal dose delivered with nebulizers and mostly occurred in proximal airways. Further studies are needed to link substantial concentrations of antibiotics in infected pulmonary fluids to pulmonary deposition. The administration technique with nebulizers should be improved in ventilated patients in order to ensure an efficient but safe, feasible and reproducible technique. Twenty-six clinical and ten experimental studies were... Read More | Comment
Upvote Story 5
The use of active noise cancellation, as delivered by noise-cancelling headphones, is associated with a significant reduction in noise exposure in our model of noise exposure in a cardiac ICU. This is the first study to look at the potential effectiveness of active noise control in adult patients in an intensive care environment and shows that active noise control is a candidate technology to reduce... Read More | Comment
Upvote Story 8
This real-life study emphasizes oseltamivir efficacy on in-hospital outcome when administrated within 2 days of the onset of symptoms. Even if physicians’ awareness of the influenza disease has been undeniably enhanced since the last pandemic, many efforts are still required to improve influenza-infected patient management in ICUs, including early oseltamivir administration. Read More | Comment
Upvote Story 9
When patients with advanced cancer near the end of their life, it is important for physicians, nurses, and other health care personnel to respect and dignify the dying process of the patient. This requires a shift in focus from medical intervention to personalization of care to meet the subjective needs of patients and families, including coordination of care, symptom management, communication, and education; emotional and... Read More | Comment
Upvote Story 7
Quieter, non-ICU wards have as many SLCs as ICUs do, which has implications for quality improvement measurements. Efforts to further reduce average noise levels might be counterproductive. Light levels in the hospital (ICU and non-ICU) may not be optimal for maintenance of a normal circadian rhythm for most people. The ICU rooms were louder than non-ICU wards; hourly averages ranged from 56.1 ± 1.3 dB... Read More | Comment
Upvote Story 13
Sepsis is a leading cause of death in the United States, but the mechanisms underlying sepsis-induced immune dysregulation remain poorly understood. 2B4 (CD244, SLAM4) is a cosignaling molecule expressed predominantly on NK cells and memory CD8+ T cells that has been shown to regulate T cell function in models of viral infection and autoimmunity. In this article, we show that 2B4 signaling mediates sepsis lymphocyte... Read More | Comment
Upvote Story 6
Critically injured patients presenting to nontrauma hospitals require timely transfer to trauma centers; however, the transfer process varies and differences in outcomes for patients from trauma centers are unknown. We evaluated regional trauma outcomes after the local Emergency Medicine System implementation of policies that allow the expedited transfer of critically injured trauma patients or "rapid retriage" from nontrauma hospitals to trauma centers. Read More | Comment
Upvote Story 4
Increased oestrogen is a strong epidemiological risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic defects. In addition, oestrogens drive penetrance in mice carrying mutations in bone morphogenetic protein receptor type II (BMPR2), the cause of most heritable PAH. The goal of the present study was to determine whether inhibition of oestrogens was effective in the treatment of PAH in... Read More | Comment
Upvote Story 10
In the first large study to look at how blood transfusions from previously pregnant women affect recipients’ health, researchers discovered men under 50 were 1.5 times more likely to die in the three years following a transfusion if they received a red blood cell transfusion from a woman donor who had ever been pregnant. This amounts to a 2 percent increase in overall mortality each... Read More | Comment
Upvote Story 14
In the largest well-controlled study of acute kidney injury (AKI) following contrast administration in the ED to date, intravenous contrast was not associated with an increased frequency of acute kidney injury. Rates of acute kidney injury were similar among all groups. Contrast administration was not associated with increased incidence of acute kidney injury (contrast-induced nephropathy criteria odds ratio=0.96, 95% confidence interval 0.85 to 1.08; and... Read More | Comment
Upvote Story 9
With growing interest in understanding muscle atrophy and function in critically ill patients and survivors, ultrasound is emerging as a potentially powerful tool for skeletal muscle quantification. However, there are key challenges that need to be addressed in future work to ensure useful interpretation and comparability of results across diverse observational and interventional studies, according to a research paper published in Annals of the American... Read More | Comment