Association Between Premorbid Beta-Blocker Exposure and Sepsis Outcomes

Association Between Premorbid Beta-Blocker Exposure and Sepsis Outcomes

This study suggests that β-blocker exposure prior to sepsis, especially to noncardioselective β blockers, may be associated with better outcome. The findings suggest prospective evaluation of β-blocker use in the management... read more

Bodily Pain in Survivors of ARDS

Bodily Pain in Survivors of ARDS

Nearly half of acute respiratory distress syndrome (ARDS) survivors reported bodily pain at 6- and 12-month follow-up; one-third reported pain at both time points. Pre-ARDS unemployment, smoking history, and in-ICU opioid... read more

New Therapy Could Protect Lung Function in COVID-19 Patients

New Therapy Could Protect Lung Function in COVID-19 Patients

There is an urgent need for new drugs for ARDS patients, including those with COVID-19. ARDS in influenza-infected mice is associated with reduced levels of liponucleotides (essential precursors for de novo phospholipid synthesis)... read more

Persistent Neuropsychiatric Symptoms After COVID-19

Persistent Neuropsychiatric Symptoms After COVID-19

The nature and extent of persistent neuropsychiatric symptoms after COVID-19 are not established. To help inform mental health service planning in the pandemic recovery phase, we systematically determined the prevalence of... read more

Trend and Pattern of 100 ARDS Patients Teferred for VV ECMO Treatment

Trend and Pattern of 100 ARDS Patients Teferred for VV ECMO Treatment

Referral to specialized center for venovenous (VV) ECMO treatment should be considered expeditiously in case of refractory ARDS, which is often lethal. Transport of unstable patients, although challenging, is feasible and... read more

Ultrasound Grayscale Analysis in ARDS COVID-19

Ultrasound Grayscale Analysis in ARDS COVID-19

Recent evidence regarding the novel coronavirus disease 2019 (COVID19) is growing in describing the characteristics of this disease, with main focus on lung morphology. Few data are available regarding the peripheral and... read more

Promoting Evidence-Based Practice in ARDS

Promoting Evidence-Based Practice in ARDS

There is a dearth of literature addressing interventions to improve implementation of evidence-based practices in acute respiratory distress syndrome (ARDS). Existing interventions to improve clinician knowledge and facilitate... read more

Use of Procalcitonin During the First Wave of COVID-19

Use of Procalcitonin During the First Wave of COVID-19

A minority of patients presenting to hospital with COVID-19 have bacterial co-infection. Procalcitonin testing may help identify patients for whom antibiotics should be prescribed or withheld. This study describes the... read more

Prone Positioning of Nonintubated Patients with COVID-19

Prone Positioning of Nonintubated Patients with COVID-19

Despite the significant variability in frequency and duration of prone positioning and respiratory supports applied, prone positioning was associated with improvement in oxygenation variables without any reported serious... read more

Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Johnson & Johnson Vaccination

Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Johnson & Johnson Vaccination

The initial 12 US cases of Cerebral Venous Sinus (CVST) with thrombocytopenia after Ad26.COV2.S (Janssen/Johnson & Johnson) vaccination represent serious events. This case series may inform clinical guidance as Ad26.COV2.S... read more

Association Between Pre-Existing Respiratory Disease and COVID-19

Association Between Pre-Existing Respiratory Disease and COVID-19

Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its prevalence in the general population. The aim of this study was to assess whether... read more

Decreased Mortality in ARDS Patients Treated with Corticosteroids

Decreased Mortality in ARDS Patients Treated with Corticosteroids

The use of glucocorticoids might result in reduced mortality in patients with ARDS. Glucocorticoids might be recommended as an adjunct to standard care for ARDS; however, the optimal dose and duration of steroid therapy remains... read more

Cerebral Oxygen Saturation and Autoregulation During Hypotension in Extremely Preterm Infants

Cerebral Oxygen Saturation and Autoregulation During Hypotension in Extremely Preterm Infants

Dopamine had no effect on rScO2 compared to placebo in hypotensive infants. Hypotension and cerebral hypoxia are associated with early intraventricular hemorrhage or death. Prospective cohort study of blinded rScO2 measurements... read more

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

COVID-19 patients with pre-existing coronary artery disease represented a higher abnormal percentage of cardiac markers, accompanied by high mortality and ICU admission rate. BNP together with hs-TNI, α- HBDH, CK-MB and... read more