Tag: study
Health Coaching to Increase Appropriate Inhaler Use in COPD
Health coaching may provide a scalable model that can improve care for people living with chronic obstructive pulmonary disease (COPD). Baseline adherence and inhaler technique were uniformly poor and did not differ by... read more
Lifting the Impenetrable Veil: From Yellow Fever to Ebola Hemorrhagic Fever & SARS
This book tells their communal story, the story of medical history, entomology, vector-borne diseases, virology, epidemiology and related fascinating but little recognized disciplines Interweaving his own personal stories... read more
Global, Regional, and National Sepsis Incidence and Mortality: 1990-2017
Globally, there were an estimated 60.2 million cases of sepsis in 1990 and 48.9 million cases of sepsis in 2017. This change represents a decrease of 18.8%. Of all incident cases of sepsis in 2017, 33.1 million occurred... read more
Soluble Urokinase Receptor and AKI
The authors concluded that high suPAR levels were associated with Acute Kidney Injury (AKI) in various clinical and experimental contexts. This cohort study reports that suPAR was associated with subsequent AKI in several... read more
A Team Response to a Potential Killer: Sepsis
Our bodies are very good at fighting infection. The immune system reacts and attacks bacteria and viruses that make us sick. But sometimes the immune reaction is so strong that it damages the body. This is called a septic... read more
Prone Positioning Monitored by Electrical Impedance Tomography in Patients with Severe ARDS on VV-ECMO
Prone positioning (PP) during veno-venous ECMO is feasible, but its physiological effects have never been thoroughly evaluated. Our objectives were to describe, through electrical impedance tomography (EIT), the impact of... read more
Tranexamic Acid Has Nominal Benefit for TBI
Studies examining the use of tranexamic acid (TXA) inescapably seem to pit our rigorous methodological demons against our practical clinical angels. The CRASH-2 trial randomized 20,211 adult trauma patients presenting... read more
A Prospective Observational Study of High-Dose Intrathecal Diamorphine in Laparoscopic Bariatric Surgery
We have demonstrated that neuraxial blockade is a simple, practical, and feasible technique to adopt. Our case series demonstrated a high level of patient acceptability. 50 patients were included. 11 patients (22%) had... read more
The ABCDE Bundle Associated with Significant Reductions in Duration of Mechanical Ventilation
The focus on long-term consequences of critical illness has intensified with increasing ICU utilization and survivorship. Post Intensive Care Syndrome (PICS) is increasingly recognized and has profound and long-lasting negative... read more
Risk Factors for Septicemia Deaths and Disparities in a Longitudinal US Cohort
In this cohort, the major risk factors for septicemia death were similar to those for other causes of death, there was approximately a 2-fold Black-White disparity in septicemia deaths, and the strongest mediators of this... read more
Conservative vs. Interventional Treatment for Spontaneous Pneumothorax
Although the primary outcome was not statistically robust to conservative assumptions about missing data, the trial provides modest evidence that conservative management of primary spontaneous pneumothorax was noninferior... read more
Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data
Systemic inflammatory response syndrome and Sequential Organ Failure Assessment initially identified distinct populations. Using systemic inflammatory response syndrome resulted in earlier electronic health record sepsis... read more
Best Practice Advisories Improve Sedation Protocol Compliance in the ICU
Best practice advisories can be effectively used in ICUs to improve sedation protocol compliance and may mitigate potential propofol-related hazardous conditions. Best practice advisories should undergo continuous quality... read more
Association Between Hypothermia/Ischemia Ratio and Functional Outcome
Although a larger hypothermia/ischemia ratio was associated with good functional outcome after out-of-hospital cardiac arrest in this cohort, this association is primarily driven by duration of time to return of spontaneous... read more