Time from Infiltrate on Chest Radiograph to VV ECMO in COVID-19 Affects Mortality

Time from Infiltrate on Chest Radiograph to VV ECMO in COVID-19 Affects Mortality

Venovenous extracorporeal membrane oxygenation (VV ECMO) has been used to treat severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome; however, patient selection criteria have evolved throughout the... read more

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest

Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitated from cardiac arrest did not result in significantly different percentages of patients dying or having severe disability... read more

Association of Vancomycin Plus Piperacillin-tazobactam with Early Changes in Creatinine vs. Cystatin C

Association of Vancomycin Plus Piperacillin-tazobactam with Early Changes in Creatinine vs. Cystatin C

Although dozens of studies have associated vancomycin + piperacillin–tazobactam with increased acute kidney injury (AKI) risk, it is unclear whether the association represents true injury or a pseudotoxicity characterized... read more

Feed Intolerance Reversal by Prokinetics Improves Survival in Critically Ill Cirrhosis Patients

Feed Intolerance Reversal by Prokinetics Improves Survival in Critically Ill Cirrhosis Patients

Feed intolerance (FI) is common in critically-ill cirrhosis patients and non-resolution carries high mortality. Early recognition and treatment with prokinetics is recommended to improve short-term survival. Of the 1,030... read more

Plasma Exchange in the ICU

Plasma Exchange in the ICU

In this narrative review, we discuss the relevant issues of therapeutic plasma exchange (TPE) in critically ill patients. For many conditions, the optimal indication, device type, frequency, duration, type of replacement... read more

Septic Shock Developing Later During Hospital Stay Associated with Higher Mortality

Septic Shock Developing Later During Hospital Stay Associated with Higher Mortality

In-hospital mortality continued to rise as admission-shock-onset-time increased in patients with septic shock. No clear dichotomization between early and late septic shock could be ascertained, and this categorization may... read more

Care Step Pathway an Effective Tool For Clinicians Caring for Mechanical Ventilated COVID-19 Patients

Care Step Pathway an Effective Tool For Clinicians Caring for Mechanical Ventilated COVID-19 Patients

The Care Step Pathway (CSP) described in this article was developed to increase awareness of the potential association of SARS-CoV-2 infection with invasive fungal infections, particularly pulmonary aspergillosis. The... read more

Dexmedetomidine vs. Propofol Sedation in Critically Ill Adults Requiring Mechanical Ventilation

Dexmedetomidine vs. Propofol Sedation in Critically Ill Adults Requiring Mechanical Ventilation

Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and the risk of delirium in cardiac surgical patients. It also significantly... read more

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis in adolescents and young adults following the administration of coronavirus disease 2019 (COVID‐19) mRNA vaccines has been reported. Vaccination of 12–16‐year‐old adolescents with Comirnaty (tozinameran,... read more

Improving Outcomes in Patients with Difficult Airways

Improving Outcomes in Patients with Difficult Airways

Evidence indicates that the airway community has successfully conquered the anatomically difficult airway, as these patients are managed safely with a low incidence of morbidity and mortality. In contrast, the literature... read more

The Effect of ICU Diaries on PTSD, Anxiety, and Depression

The Effect of ICU Diaries on PTSD, Anxiety, and Depression

Providing an ICU diary to patients admitted to the ICU reduced the rate of posttraumatic stress disorder (PTSD) symptoms compared with usual care. We included 7 RCTs. Patients who received a diary during the ICU admission... read more

Advanced Bleeding Control in Combat Casualty Care

Advanced Bleeding Control in Combat Casualty Care

Consensus was reached on the contents of a standard bleeding control toolbox, where it should be available, providers and training requirements, international registries and guidelines, and potential indications for REBOA... read more

Etomidate, Adrenal Insufficiency and Mortality Associated with Severity of Illness

Etomidate, Adrenal Insufficiency and Mortality Associated with Severity of Illness

Whereas etomidate causes adrenal insufficiency, it was not shown to increase mortality in many analyzed here in ICU settings. However, etomidate associated relative mortality rates increased progressively and correlated with... read more

Pulmonary Aeration and Posterior Collapse Assessed by Electrical Impedance Tomography in Healthy Children

Pulmonary Aeration and Posterior Collapse Assessed by Electrical Impedance Tomography in Healthy Children

The aim of this study was to evaluate the changes in the lung aeration estimated by electrical impedance tomography as the end-expiratory lung impedance after anesthesia induction in pediatric patients. This was a prospective,... read more