Tag: TBI

Upvote Story 6
A biomarker test based on the presence of two proteins in the blood appears to be suitable for ruling out significant intracranial injuries in patients with a history of mild traumatic brain injury (TBI) without the need for a CT head scan, according to data presented at the annual meeting of the American College of Emergency Physicians. A biomarker suitable for ruling out significant brain... Read More | Comment
Upvote Story 14
Often misdiagnosed and misunderstood, traumatic brain injury (TBI) may be a life-altering event which can produce a wide range of symptoms affecting physical as well as psychological health. Indeed, all senses can be affected, especially sight and sound, producing errors in judgment, loss of memory, and difficulty processing information. Now, a physician shares her personal journey with TBI after suffering a life changing accident. In... Read More | Comment
Upvote Story 8
Dr. Larry Komer and Joan Chandler Komer offer new hope to those with brain injuries. Millions of people of all ages experience concussions. Many others have a more serious event known as a traumatic brain injury. Battlefield injuries often include concussions or a TBI. These brain injuries can lead to a complex condition known as PTSD that can alter a person’s life, family and community.... Read More | Comment
Upvote Story 8
Severe traumatic brain injury is a clinically heterogeneous disease that can be accompanied by a range of neurologic impairment and a variety of injury patterns at presentation. This secondary analysis of prospectively collected data identifies several characteristics associated with outcome among children with severe traumatic brain injury. Future, larger trials are needed to better characterize phenotypes within this population. Baseline, clinical, and CT characteristics of... Read More | Comment
Upvote Story 6
This book collects and synthesizes the latest thinking on the condition in its variety of cognitive and behavioral presentations, matched by a variety of clinical responses. Acknowledging the continuum of injury and the multi-stage nature of recovery, expert contributors review salient research data and offer clinical guidelines for the neuropsychologist working with TBI patients, detailing key areas of impairment, brief and comprehensive assessment methods and... Read More | Comment
Upvote Story 13
Among patients with severe traumatic brain injury (TBI), early prophylactic hypothermia compared with normothermia did not improve neurologic outcomes at 6 months. These findings do not support the use of early prophylactic hypothermia for patients with severe traumatic brain injury. Among 511 patients who were randomized, 500 provided ongoing consent (mean age, 34.5 years [SD, 13.4]; 402 men [80.2%]) and 466 completed the primary outcome... Read More | Comment
Upvote Story 11
In this prospective cohort study of Danish ICU patients, we found significantly reduced cognitive function for intensive care patients 3 and 12 months after discharge. We included 161 patients, 79 patients had a 3-month and 53 a 12-month follow-up visit. The primary reasons for not being visited at 3-month were death (44 patients), decline (26 patients), or transferal to another ICU (6 patients). Three and... Read More | Comment
Upvote Story 15
Teleologically, the mammalian brain has evolved to be the central component of life. It coordinates afferent and efferent neural pathways, integrates neurohormonal responses and, in humans, produces higher cortical effects that augment developmental and protective processes. Despite this vital role for human survival, the brain is profoundly vulnerable to injury and is in many ways set up to fail with devastating consequences for the patient.... Read More | Comment
Upvote Story 4
Lidocaine has weak evidence to support its ICP blunting effects. Fentanyl may be a better choice. Ketamine is a reasonable alternative to etomidate during induction. No differnce in mortality exists between usage of succinylcholine or rocuronium. There may be a mortality difference in a subset of patients with severe head injury. More research is needed. Read More | Comment
Upvote Story 7
Consider using balanced fluids in your ED unless you are treating a patient at risk for cerebral edema, or a patient with a chloride responsive metabolic alkalosis, e.g. from gastric losses. Although the superiority of balanced fluids to NS is still debated, balanced solutions have many physiologic advantages. The commonly used balanced fluids, LR and Plasma-Lyte, do not contain supraphysiologic chloride and are buffered by... Read More | Comment
Upvote Story 6
The role of speech and language therapists (SLTs) in critical care can be unclear so this article sets out the scope of practice to increase awareness of the value of SLTs as part of the wider multidisciplinary team. Speech and language therapists (SLT) are trained to deliver specialist clinical services to adults with a broad range of disorders, including hearing impairment, motor speech disorders (dysarthria,... Read More | Comment
Upvote Story 20
Ketamine alters hippocampal cell proliferation after traumatic brain injury (TBI). Surprisingly, these changes were associated with improvement in a neurogenesis-related behavioral recall task, suggesting a possible benefit from ketamine administration after traumatic brain injury in mice. Future studies are needed to determine generalizability and mechanism. Traumatic brain injury was induced in mice using a controlled cortical impact injury, after which mice (N = 118) received... Read More | Comment
Upvote Story 8
Currently, TBI management is guided by clinical histories and neuroimaging techniques. While these techniques may be advanced, they are more costly than serum analysis, involve exposure to ionizing radiations, and have certain limitations when assessing brain damage severity. The ideal biomarker would stratify patients based on their severity, identifying patients with poorer prognosis and greater need for treatment before the patient’s condition worsens. Read More | Comment
Upvote Story 7
1. Only neurointensivists should care about the brain. 2. Clinical examination of neurocritically ill patients is impossible. 3. We should no longer monitor ICP in traumatic brain injury (TBI). 4. The threshold to treat ICP is 20 or 22mmHg. 5. Ketamine increases the ICP. 6. Subarachnoid haemorrhage (SAH) patients should get ‘triple H’ therapy. 7. There is no need to control the temperature after cardiac... Read More | Comment
Upvote Story 6
Intracranial hypertension (ICH) is a major cause of death after traumatic brain injury (TBI). Continuous hyperosmolar therapy (CHT) has been proposed for the treatment of ICH, but its effectiveness is controversial. We compared the mortality and outcomes in patients with TBI with ICH treated or not with CHT. CHT for the treatment of posttraumatic ICH was associated with improved adjusted 90-day survival. This result was... Read More | Comment