Treating Hypoxia in Discharged COVID-19 Patients

Treating Hypoxia in Discharged COVID-19 Patients

The ICU technique of placing a hypoxic patient in a prone position is being widely used to care for COVID-19 patients in respiratory distress to improve oxygenation and possibly to avoid intubation. The COVID-19 pandemic... read more

Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions

Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions

Critically ill COVID-19 patients have highly complex medical needs during transport. Critical care transfer of COVID-19-positive patients by civilian HEMS services, including air transfer, can be achieved safely with specific... read more

The Value of Echocardiography Combined with Lung Ultrasound to Evaluate COVID-19 Pneumonia

The Value of Echocardiography Combined with Lung Ultrasound to Evaluate COVID-19 Pneumonia

In COVID-19 pneumonia patients, the pulmonary arterial pressure and LUS are positively correlated. For those who are unable to be transferred or relocated, the pulmonary arterial pressure may be measured to reflect the degree... read more

Association Between Incident Delirium Treatment with Haloperidol and Mortality in Critically Ill Adults

Association Between Incident Delirium Treatment with Haloperidol and Mortality in Critically Ill Adults

Treatment of incident delirium and its symptoms with haloperidol may be associated with a dose-dependent improvement in survival. Future randomized trials need to confirm these results. Patients were evaluated tid for... read more

The Role of Antiviral Treatment in the COVID-19 Pandemic

The Role of Antiviral Treatment in the COVID-19 Pandemic

US Food and Drug Administration (FDA) issued an emergency use authorisation for Pfizer's COVID-19 antiviral, Paxlovid few weeks ago. Trial results released by the manufacturer indicate that the drug cuts the risk of hospitalisation... read more

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support... read more

WHO Recommends Two New Drugs for COVID-19 Treatment

WHO Recommends Two New Drugs for COVID-19 Treatment

WHO has recommended two new drugs for COVID-19, providing yet more options for treating the disease. The extent to which these medicines will save lives depends on how widely available and affordable they will be. The... read more

Remdesivir Treatment for Hospitalized COVID-19 Patients in Canada

Remdesivir Treatment for Hospitalized COVID-19 Patients in Canada

Remdesivir, when compared with standard of care, has a modest but significant effect on outcomes important to patients and health systems, such as the need for mechanical ventilation. Across 52 Canadian hospitals, we randomized... read more

Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen

Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen

Remdesivir treatment increased the likelihood of clinical improvement in COVID-19 patients on low-flow oxygen or no oxygen, according to a new study by the Johns Hopkins University School of Medicine, the Johns Hopkins Bloomberg... read more

How One Patient Was Treated for a Stroke Via Telemedicine

How One Patient Was Treated for a Stroke Via Telemedicine

A patient believed to have suffered a stroke typically gets transported to the nearest emergency room for tests to determine the best course of action. Telemedicine at Johns Hopkins Medicine enabled one patient to have... read more

Long-Term Opioid Prescription Linked to Higher Risk of Hepatitis C

Long-Term Opioid Prescription Linked to Higher Risk of Hepatitis C

Exposure to long-term prescription opioid therapy was linked to a three times higher risk of HCV seroconversion compared to individuals who were prescription opioid-naïve or acute. Prescription opioid use is associated... read more

Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19

Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19

The results of this randomized clinical trial demonstrated that ciclesonide did not achieve the primary efficacy end point of reduced time to alleviation of all COVID-19–related symptoms. A total of 413 participants... read more

Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection

Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection

A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here, we studied individuals with LC compared to... read more

Effect of Early Fluvoxamine Treatment Among COVID-19 Patients

Effect of Early Fluvoxamine Treatment Among COVID-19 Patients

Treatment with fluvoxamine (100 mg twice daily for 10 days) among high-risk outpatients with early diagnosed COVID-19 reduced the need for hospitalisation defined as retention in a COVID-19 emergency setting or transfer to... read more