Thousands Who Got COVID-19 in March Are Still Sick

Thousands Who Got COVID-19 in March Are Still Sick

COVID-19 has existed for less than six months, and it is easy to forget how little we know about it. The standard view is that a minority of infected people, who are typically elderly or have preexisting health problems,... read more

Sharing Data is the Key to Unlocking Remdesivir Challenges

Sharing Data is the Key to Unlocking Remdesivir Challenges

Critical care teams should consider using remdesivir to treat patients with severe acute SARS-CoV-2 infection, but supply of the drug is limited and best practices for maximizing its effectiveness are not completely understood. The... read more

Hydroxychloroquine or Azithromycin for COVID-19 Treatment

Hydroxychloroquine or Azithromycin for COVID-19 Treatment

The use of hydroxychloroquine, azithromycin, or both were not associated with differences in in-hospital mortality. Cardiac arrest was more likely in patients receiving hydroxychloroquine and azithromycin. In this retrospective,... read more

Risk Score for Development of Critical Illness in Patients with COVID-19

Risk Score for Development of Critical Illness in Patients with COVID-19

In this study, we developed a risk score and web-based calculator to estimate the risk of developing critical illness among patients with COVID-19 based on 10 variables commonly measured on admission to the hospital. Estimating... read more

Rapid Development of an Inactivated Vaccine Candidate for COVID-19

Rapid Development of an Inactivated Vaccine Candidate for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more

What’s Working for COVID-19 Patients in the Epicenter

Our large tertiary care ED in Queens, NY, usually sees more than 100,000 adults a year. As we write this, we have 850 COVID-19-likely or -positive patients (several hundred above our bed capacity just one month ago), more... read more

COVID-19: Two More Trials Just Published on Remdesivir

COVID-19: Two More Trials Just Published on Remdesivir

Currently, there are no approved medications for the treatment of COVID-19, but, there are many investigational agents that have shown antiviral activity against SARS-CoV-2 in vitro. Unfortunately in vitro studies do... read more

Pandemic Science Out of Control

Pandemic Science Out of Control

A toxic legacy of poor-quality research, media hype, lax regulatory oversight, and vicious partisanship has come home to roost in the search for effective treatments for COVID-19. The rush to offer unproven treatments... read more

Low-dose Dopamine in Patients with Early Renal Dysfunction

Low-dose Dopamine in Patients with Early Renal Dysfunction

Administration of low-dose dopamine by continuous intravenous infusion to critically ill patients at risk of renal failure does not confer clinically significant protection from renal dysfunction. The groups assigned dopamine... read more

Expert Panel Develops NIH Treatment Guidelines for COVID-19

Expert Panel Develops NIH Treatment Guidelines for COVID-19

A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COVID-19). These guidelines, intended for healthcare providers, are based on published and preliminary... read more

Palliative Care Considerations For Patients With Cardiovascular Disease Under COVID-19

Palliative Care Considerations For Patients With Cardiovascular Disease Under COVID-19

COVID-19 has dramatically altered our world, health care systems and supply chains. Older adults with cardiovascular disease especially those over 80 years suffer disproportionately. This pandemic has stressed the capacity... read more

Influenza: The Hundred-Year Hunt to Cure the Deadliest Disease in History

Influenza: The Hundred-Year Hunt to Cure the Deadliest Disease in History

A veteran ER doctor explores the troubling, terrifying, and complex history and present-day research of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for... read more

Plasma Transfusion Shows Promise for COVID-19 Treatment

Plasma Transfusion Shows Promise for COVID-19 Treatment

Donor blood plasma from people who have recovered from COVID-19 appears to work as a treatment for the virus, a new analysis has revealed. In this preliminary uncontrolled case series of 5 critically ill patients with... read more

Chinese Frontline Anesthesiologists Share COVID-19 Treatment Experience

Chinese Frontline Anesthesiologists Share COVID-19 Treatment Experience

Anesthesiologists are crucial in the treatment of COVID-19 patients, with their role encompassing anesthesia, intensive care, pain treatment and more. The job is of high risk, with medical staff at risk of getting infected... read more