Anticipating the Future of the COVID-19 Pandemic

Anticipating the Future of the COVID-19 Pandemic

The initial instance of a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was observed in December 2019 in the city of Wuhan, China. Subsequently, the virus disseminated expeditiously across the globe,... read more

Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU

Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU

We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more

Estimating Seroprevalence of COVID-19 Infection After Omicron Outbreak

Estimating Seroprevalence of COVID-19 Infection After Omicron Outbreak

This study aimed to investigate the seroprevalence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibodies among individuals aged 18 years and older. Population-based study was conducted within the Arizona... read more

Increased Risk of Hospitalization in Celiac Disease with COVID-19 Infection Is Mitigated by Vaccination

Increased Risk of Hospitalization in Celiac Disease with COVID-19 Infection Is Mitigated by Vaccination

Celiac disease (CD) patients with COVID-19 have a higher risk of hospitalization compared with non-CD referents. This risk is mitigated by vaccination in CD patients as it is in non-CD referents. ICU requirement occurred... read more

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis in adolescents and young adults following the administration of coronavirus disease 2019 (COVID‐19) mRNA vaccines has been reported. Vaccination of 12–16‐year‐old adolescents with Comirnaty (tozinameran,... read more

Myopericarditis Following COVID-19 Vaccination and Non-COVID-19 Vaccination

Myopericarditis Following COVID-19 Vaccination and Non-COVID-19 Vaccination

The overall incidence of myopericarditis from 22 studies (405,272,721 vaccine doses) was 33·3 cases (95% CI 15·3–72·6) per million vaccine doses, and did not differ significantly between people who received COVID-19... read more

Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England

Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England

The risk of severe outcomes following SARS-CoV-2 infection is substantially lower for omicron than for delta, with higher reductions for more severe endpoints and significant variation with age. Underlying the observed risks... read more

Ethnic Differences in COVID-19 Mortality in the 2nd and 3rd Waves of the Pandemic in England

Ethnic Differences in COVID-19 Mortality in the 2nd and 3rd Waves of the Pandemic in England

Public health strategies to increase vaccination uptake in ethnic minority groups could reduce disparities in COVID-19 mortality that cannot be accounted for by pre-existing risk factors. Age-adjusted HRs of death involving... read more

Risk Factors for Severe COVID-19 Outcomes Among Adults Who Completed a Primary COVID-19 Vaccination

Risk Factors for Severe COVID-19 Outcomes Among Adults Who Completed a Primary COVID-19 Vaccination

In this analysis of data from 465 U.S. health care facilities, severe COVID-19 outcomes (i.e., respiratory failure, ICU admission, or death) were rare among adults aged ≥18 years after primary vaccination. These findings... read more

Healthcare Worker Safety and COVID-19

Healthcare Worker Safety and COVID-19

It had been apparent from the start of the pandemic that both patients and healthcare workers are at significant risk of acquiring COVID-19 in hospitals. In an early report from Wuhan more than 40% of infections were hospital-acquired,... read more

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are... read more

Risk Factors for Severe COVID-19 in Children

Risk Factors for Severe COVID-19 in Children

Results identify children at potentially higher risk of severe disease who may benefit from COVID-19 prevention efforts, including vaccination. Rates of severe COVID-19 establish a baseline for monitoring changes in pediatric... read more

How protein-based COVID vaccines could change the pandemic

How protein-based COVID vaccines could change the pandemic

Unlike the relatively new technologies that the mRNA and viral-vector COVID-19 shots are based on, protein vaccines have been used for decades to protect people from hepatitis, shingles and other viral infections. To... read more

Not all COVID waves look the same. Here’s a snapshot of the Delta surge

Not all COVID waves look the same. Here’s a snapshot of the Delta surge

Waves of Covid can give you an awful sense of déjà vu. As "Hot Vax Summer" gave way early to Delta-anxious fall, you could be forgiven for feeling a familiar sense of dread, not so different from what you’d felt before... read more