Metabolic-based Biomarkers Have Potential to Triage Children with Sepsis

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A new study has validated potential biomarkers for a sepsis-triage model to distinguish sepsis patients requiring care in the pediatric intensive care unit (PICU) from sepsis identified in the pediatric emergency department (PED) that does not require ICU admission. The study, led by Beata Mickiewicz and colleagues from the University of Calgary and University of Alberta, took serum and plasma samples from children aged 1-23 months presenting with sepsis to the PICU (n=46) or who presented to the pediatric emergency department with (n=58) and without sepsis (n=19).

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