Optimal Timing of RRT in Patients with AKI in the Context of Sepsis

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AKI

Among 620 patients enrolled in AKIKI, 494 (80%) had sepsis and 413 (67%) septic shock. This can help to suggest recommendations in septic patients with AKI. AKIKI showed no significant difference in mortality between early and delayed RRT strategy. The early strategy was responsible for increased incidence of catheter infection and delayed recovery of renal function. It would be more logical to conclude that, pending results of ongoing studies, the present evidence is in favor of delayed initiation.

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