Fluid Personalization and Vasopressor Decisions in Early Sepsis Management

Fluid Personalization and Vasopressor Decisions in Early Sepsis Management

In this randomized vignette survey study of US critical care clinicians, we found that fluid volume already received was associated with the largest changes in decisions to administer additional fluids or initiate vasopressors... read more

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Major traumatic hemorrhage is potentially preventable with rapid hemorrhage control and improved resuscitation techniques. The time from injury to hospital, resuscitation, diagnosis, and definitive bleeding control should... read more

Scientific Study Validates Usability of Post-ICU Digital Diary for Families of ICU Patients

Scientific Study Validates Usability of Post-ICU Digital Diary for Families of ICU Patients

In a groundbreaking pilot study, "The usability of a digital diary from the perspectives of intensive care patients’ relatives", researchers have unequivocally confirmed the practicality and effectiveness of Post-ICU for... read more

AKI Risk Factors in ICU Patients Using Colistin

AKI Risk Factors in ICU Patients Using Colistin

Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more

Anticipating the Future of the COVID-19 Pandemic

Anticipating the Future of the COVID-19 Pandemic

The initial instance of a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was observed in December 2019 in the city of Wuhan, China. Subsequently, the virus disseminated expeditiously across the globe,... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more

VTE in Critically Ill Adult Patients with Hematologic Malignancy

VTE in Critically Ill Adult Patients with Hematologic Malignancy

Among patients with hematologic malignancy, critical illness and certain baseline characteristics were associated with a higher incidence of venous thromboembolism (VTE). Among 76,803 eligible patients (mean age 67 years... read more

Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19

Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19

Metagenomic next-generation sequencing (mNGS) has a significant value in the diagnosis of Chlamydia psittaci infection. Timely treatment of omadacycline can improve prognosis and provide a promising new option for the treatment... read more

Sepsis Management: PIRO and MODS

Sepsis Management: PIRO and MODS

This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent... read more

Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU

Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU

We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more

Haloperidol vs. Placebo in ICU Patients with Delirium

Haloperidol vs. Placebo in ICU Patients with Delirium

We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. In acutely admitted adult ICU patients with delirium, haloperidol treatment... read more

Extracorporeal Life Support for Adults

Extracorporeal Life Support for Adults

This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more

10 Reasons for Pharmacy Professionals Presence in the ICU

10 Reasons for Pharmacy Professionals Presence in the ICU

The momentum exists for establishing and expanding ICU pharmacy practice throughout Europe. A first step should be a White Paper, describing the roles and key priorities for ICU pharmacy professionals. Education should... read more

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more