The purpose of this literature review was to investigate the major barriers nurses face when it is necessary to seek additional assistance and resources by calling the rapid response team (RRT) in order to manage and stabilize... Read More

In patients with STEMI given crushed ticagrelor before PCI, using IV acetaminophen instead of IV fentanyl as a painkiller did not increase pain levels or platelet reactivity and prevented delay of ticagrelor’s effects,... Read More

Glucocorticoids probably reduce mortality and mechanical ventilation in patients with COVID-19 compared with standard care. The effectiveness of most interventions is uncertain because most of the randomised controlled trials... Read More

The primary efficacy outcome was the development of a major venous thromboembolic event such as symptomatic distal or proximal deep-vein thrombosis, asymptomatic deep vein thrombosis, pulmonary embolism or venous thromboembolism–related... Read More

Confusion between inhaled versus intravenous routes for pulmonary vasodilators. For optimal clinical benefit (especially regarding oxygenation), these agents must be given via an inhaled route. The misconception that inhaled... Read More

Stepping on to the ICU during this period was like entering another world. In a way intensive care has always seemed like a place removed from life outside said Mike Brunner, an intensive care doctor at Northwick Park hospital... Read More

Extracorporeal membrane oxygenation (ECMO) causes both thrombosis and bleeding. Major society guidelines recommend continuous, systemic anticoagulation to prevent thrombosis of the ECMO circuit, though this may be undesirable... Read More

In a hospital treating COVID-19 patients, SARS-CoV-2 RNA was found widely distributed in surface and air samples. Contamination was greater in intensive care units (54/124 samples) than general wards (9/114 samples). A 100%... Read More

We found a high incidence of CAPA among critically ill COVID-19 patients and that its occurrence seems to change the natural history of disease. A total of 108 patients were enrolled. Prospective, multicentre study on adult... Read More

Using adjunctive hydrocortisone therapy yields a significant monetized benefit based on inputs from the Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock and Activated Protein C and Corticosteroids... Read More

As we start to move to the next stage of the COVID-19 pandemic, it feels like a moment to take stock. The country has gone through huge changes to our way of life over the last few months, and those changes have been mirrored... Read More

The trial objective is to determine if Continuous Positive Airway Pressure (CPAP) or High-Flow Nasal Oxygen (HFNO) is clinically effective compared to standard oxygen therapy in patients with confirmed or suspected COVID-19.... Read More

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the rapidly unfolding coronavirus disease 2019 (COVID-19) pandemic. Clinical manifestations of COVID-19 vary, ranging from asymptomatic infection to... Read More

The purpose of this study is to determine the impact of a new RN/RRT (Registered Nurse/Registered Respiratory Therapist) directed 2-step protocol to wean patients off of a ventilator. This protocol involves daily attempts... Read More

The purpose of this guideline is to help healthcare professionals deliver efficient planned care while minimising the risk of COVID-19 in the context of increasing or decreasing local prevalence. It also aims to help patients... Read More

Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually... Read More

Non-invasive respiratory support could be useful in treating COVID-19-related acute respiratory failure (ARF). A rational use of different techniques (oxygen therapy, CPAP, NIV or HFOT) by a trained pulmonologist could allow... Read More

The most popular book at ISICEM meeting. Despite increasing interest in intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) as causes of significant morbidity and mortality among the critically ill,... Read More

Currently, there is no standard process to develop Ongoing Professional Practice Evaluation and Focused Professional Practice Evaluation processes in critical care medicine. Departments and institutions can tailor metrics... Read More

The early addition of IV melatonin to asphyctic neonates is feasible and may improve long-term neurodevelopment. To our knowledge, this is the first clinical trial to analyze the administration of IV melatonin as an adjuvant... Read More