Value of Expedited Drug Approvals for Cancer Care

Value of Expedited Drug Approvals for Cancer Care

This study examines potential benefits of cancer drugs approved by the FDA on the basis of surrogate endpoints.... read more

Targeted Drug Delivery using Porous Glass Microspheres

Targeted Drug Delivery using Porous Glass Microspheres

Finding ways to improve efficiency and bioavailability is key to targeted drug delivery. Although controlled release dosage medication forms are the standard, they can have certain limitations.... read more

Study Examines Rates, Causes of ED Visits for Adverse Drug Events

Study Examines Rates, Causes of ED Visits for Adverse Drug Events

The prevalence of emergency department (ED) visits for adverse drug events (ADEs) in the United States was estimated to be four per 1,000 individuals in 2013 and 2014, and the most common drug classes involved were anticoagulants,... read more

New Screening Test Identifies Potential Therapies to Fight Drug-Resistant Bacteria

New Screening Test Identifies Potential Therapies to Fight Drug-Resistant Bacteria

Researchers at the NCATS and NIAID have found a new way to identify drugs and drug combinations that may potentially be useful in combating infections that are resistant to antibiotics. The researchers used the test to screen... read more

New discovery paves way for pancreatic cancer treatment

New discovery paves way for pancreatic cancer treatment

Patients suffering from pancreatic cancer may soon face better treatment options due to the latest discovery by Dr. Reginald Hill, who's research focuses on drugs that are already approved by the FDA.... read more

Baxter initiates late-stage study of novel therapy for acute kidney injury

Baxter initiates late-stage study of novel therapy for acute kidney injury

Baxter International commences a Phase 3 clinical trial assessing an investigational drug, Prismocitrate 18, that combines a citrate anticoagulant and renal replacement solution.... read more

FDA Approves Zinplava to Reduce Recurrence of Clostridium difficile Infection in Adult Patients

FDA Approves Zinplava to Reduce Recurrence of Clostridium difficile Infection in Adult Patients

FDA Approves Merck's ZINPLAVA (bezlotoxumab) to Reduce Recurrence of Clostridium difficile Infection (CDI) in Adult Patients Receiving Antibacterial Drug Treatment for CDI Who Are at High Risk of CDI Recurrence.... read more

Cefiderocol, A Novel Investigational Siderophore Cephalosporin, Demonstrated Potent Activity Against Multi-Drug Resistant Gram-Negative Pathogens

Cefiderocol, A Novel Investigational Siderophore Cephalosporin, Demonstrated Potent Activity Against Multi-Drug Resistant Gram-Negative Pathogens

Cefiderocol showed potent activity against Gram-negative pathogens, including carbapenem-resistant strains of Pseudomonas aeruginosa and Acinetobacter baumannii as well as carbapenem-resistant Enterobacteriaceae. The results... read more

FDA Approves sNDA for Label Changes to ADASUVE

FDA Approves sNDA for Label Changes to ADASUVE

The FDA has approved the supplemental New Drug Application for label changes to ADASUVE (loxapine) inhalation powder. ADASUVE is the first orally inhaled medication for the acute treatment of agitation associated with bipolar... read more

Impaired recycling of mitochondria in autism?

Impaired recycling of mitochondria in autism?

The new study shows that autophagy is defective in TSC. The scientists further showed that two existing classes of drugs counter the defect: the epilepsy drug carbamazepine, and drugs known as mTOR inhibitors.... read more

AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications

AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications

AHA has released a new scientific statement for managing clinically significant drug-drug interactions in patients who are prescribed statins and other agents used in the treatment of cardiovascular disease.... read more

Newer blood thinning drugs safer for reducing atrial fibrillation

Newer blood thinning drugs safer for reducing atrial fibrillation

Although warfarin has been used for nearly 60 years, researchers say newer blood thinners are a better option for lowering stroke risk among atrial fibrillation patients because they work for a shorter time with fewer side... read more