Pediatric Sepsis Phenotype with Persistent Hypoxemia, Encephalopathy, and Shock

Pediatric Sepsis Phenotype with Persistent Hypoxemia, Encephalopathy, and Shock

We derived and validated the persistent hypoxemia, encephalopathy, and shock phenotype, which is highly reproducible, clinically relevant, and associated with HTE to common adjuvant therapies in children with sepsis. We... read more

Bringing Biological ARDS Phenotypes to the Bedside with Machine-learning-based Classifiers

Bringing Biological ARDS Phenotypes to the Bedside with Machine-learning-based Classifiers

The identification of distinct phenotypes within heterogeneous disease states is a key component of personalised medicine, enabling enrichment of clinical trials, better prognostication, and delivery of tailored treatments... read more