Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults

Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults

Between Feb 6, 2014, and June 26, 2016, 1360 patients were assessed, and 672 were randomly assigned, with 222 in the placebo group, 227 in the 0·5 mg/kg ketamine group, and 223 in the 1·0 mg/kg ketamine group. There was... read more

Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery

Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery

Sodium nitroprusside (SNP) has been used clinically for decades for the treatment of hypertension associated with cardiac surgery.... read more

Prehabilitation: Preparing Patients for Surgery

Prehabilitation: Preparing Patients for Surgery

The impact of surgery leads to significant homeostatic disturbance.1 The surgical stress response is characterised by catabolism and increased oxygen demand. The extent and duration of the stress response is proportionate... read more

Nutrition in Surgery and Critical Care

Nutrition in Surgery and Critical Care

DCRI Perioperative Nutrition focuses on the study of hospital-based treatments to improve preparation and recovery from surgery, major illness, and critical care. We put real science into improving patients' lives with interventions... read more

Patients with postoperative delirium more likely to suffer dementia

Patients with postoperative delirium more likely to suffer dementia

Delirium is common in elderly hospitalized patients, affecting an estimated 14 - 56% of patients. It frequently manifests as a sudden change in behavior, with patients suffering acute confusion, inattention, disorganized... read more

An Orthopedic Surgeon Explains: Diastolic Heart Failure

An Orthopedic Surgeon Explains: Diastolic Heart Failure

It seems that every now and then we have to deal with something other than the bones. As you can imagine, this is sub-optimal at best. Because bones. Anyhow, I’ve been asked to discuss one of those issues with you, and... read more

Role of Preventability in Redefining Failure to Rescue Among Major Trauma Patients

Role of Preventability in Redefining Failure to Rescue Among Major Trauma Patients

Failure to rescue (FTR) is defined as death after a major complication and has been adopted as a measure of quality in surgical patients. Current definitions of FTR are limited because they do not account for the influence... read more

Reduced Risk of Acute Exacerbation of COPD after Bariatric Surgery

Reduced Risk of Acute Exacerbation of COPD after Bariatric Surgery

Obesity is common among individuals with chronic obstructive pulmonary disease (COPD) and associated with increased COPD morbidities. However, little is known about the impact of weight reduction on COPD-related outcomes... read more

Preoperative Cognitive Performance and Delirium Associated With Future Dementia in Older People After Cardiac Surgery

Preoperative Cognitive Performance and Delirium Associated With Future Dementia in Older People After Cardiac Surgery

Delirium after cardiac surgery commonly, occurs in 25–67 percent of patients. Delirium is a neuropsychiatric syndrome characterized by a change in cognition fluctuates, develops over a short period of time and has an underlying... read more

I’m your Anesthesiologist. Let me explain what that means

I’m your Anesthesiologist. Let me explain what that means

Anesthesiologists are the guardian angels of the operating room. Their primary purpose is to keep you alive so you can undergo whatever procedure you need. While we may only meet you shortly before we take you to the operating... read more

Analysis of Unplanned Postoperative Admissions to the ICU

Analysis of Unplanned Postoperative Admissions to the ICU

Our study is the first diverse analysis of unplanned postoperative ICU admissions in the literature across multiple specialties and practice models. We found an association of advanced age, higher ASA PS class, and duration... read more

Cardiovascular Testing and Clinical Outcomes in Emergency Department Patients With Chest Pain

Cardiovascular Testing and Clinical Outcomes in Emergency Department Patients With Chest Pain

In patients who present to the emergency department with chest pain without evidence of ischemia, is cardiac testing - noninvasive testing or coronary angiography - associated with changes in revascularization or acute myocardial... read more

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Few head-to-head treatment comparisons have sufficient evidence. Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin and mechanical devices); most reported on total deep... read more

Drug might alleviate post-surgical delirium and confusion

Drug might alleviate post-surgical delirium and confusion

To blunt postoperative pain and reduce the need for opioid drugs following surgery, anesthesiologists often give patients low doses of the drug ketamine during operations. Recent research even suggests that the drug might... read more