The COVID-19 pandemic is responsible for many hospitalizations in intensive care units (ICU), with widespread use of invasive mechanical ventilation (IMV) which exposes patients to the risk of ventilator-associated pneumonia... read more

This book offers a detailed and up-to-date overview of image-guided diagnostics in COVID-19 lung disease. A range of image-guided CT and ultrasound procedures in different chest regions are described. For each procedure,... read more

Among patients with sepsis and pre-existing cardiac disease who survived to ICU discharge, left ventricular global longitudinal systolic strain demonstrated a U-shaped association with cardiovascular outcomes through 24 months.... read more

The SOFA score possesses inadequate discriminant accuracy to be used for ventilator triage of COVID-19 patients. A better option is needed that incorporates variables specifically related to mortality in patients with COVID-19... read more

This study suggests that early intervention for patients with postintubation laryngeal injury was associated with a decreased duration of tracheostomy dependence, a higher rate of decannulation, and fewer surgical procedures... read more

The first book to tell the full story of the Covid-19 pandemic, from an NHS doctor working inside hospitals to save lives and combat the virus on the front line. Duty of Care is the first book to tell the full story of the... read more

Haloperidol and clonidine use in delirious ICU patients may be associated with reduced probability of delirium resolution. This finding, however, merits further investigation given inherent limitations of this observational... read more

Among hospitalized patients with COVID-19, a single high dose of vitamin D3, compared with placebo, did not significantly reduce hospital length of stay. The findings do not support the use of a high dose of vitamin D3 for... read more

Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Their findings, published recently... read more

ARDS is a severe disease with a high mortality rate despite ECLS therapy. Although endpoints and timing of the evaluations differed from those of the CESAR and EOLIA studies and the Extracorporeal Life Support Organization... read more

For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since... read more

CNS and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral... read more

From ideas and infections to financial crises and fake news, an “utterly timely” look at why the science of outbreaks is the science of modern life These days, whenever anything spreads, whether it’s a YouTube... read more

How common is asymptomatic COVID-19? How infectious is it? And how much does it actually contribute to overall transmission? Nicola Low spoke on behalf of herself and Muge Cevik to outline the role of asymptomatic transmission.... read more

The STUMBL score at a cut‐off of 15 predicted prolonged LOS and a score >18 predicted mortality sufficiently to be clinically useful for these outcomes. The STUMBL Score is composed of five simple predictors; patient age,... read more

Personal handheld ultrasound devices (HUDs) without direct supervision did not increase the amount of point-of-care ultrasound (POCUS) usage or improve interns’ acquisition abilities. Interns who reported performing... read more

Different weight-based fentanyl dosing rates may be required for infants and children of different ages to achieve similar plasma concentrations. Using SBS scores may guide the dosing titration of fentanyl that resulted in... read more