Prediction models are important in various fields, including medicine, physics, meteorology, and finance. Prediction models will become more relevant in the medical field with the increase in knowledge on potential predictors... Read More

Emergency Medicine: Diagnosis and Management incorporates the latest ideas and evidence base underpinning best practice emergency medicine care. This book covers a wide variety of emergencies, including general medical, critical... Read More

Blocking the action of negative muscle regulators through the activin type II receptors with bimagrumab treatment safely increased skeletal muscle mass but did not improve functional capacity in patients with COPD and low... Read More

Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body’s extreme reaction to infection. The scientists used nanotechnology... Read More

Over the past two decades, elderly patients have been more commonly admitted to ICU than can be explained solely by the demographic shift. Importantly, as with the wider population, outcomes in elderly patients admitted to... Read More

Patients who participated in an ICU mobility program had better functional status at discharge from the ICU. The other benefits of the program included better performance in the mobility tests and improved maximum voluntary... Read More

Introducing a community version of National Early Warning Score (NEWS) to clinical assessments in acute clinical care has shown benefits for both patients and staff, and could be disseminated to all community services across... Read More

More rapid completion of a 3-hour bundle of sepsis care and rapid administration of antibiotics, but not rapid completion of an initial bolus of intravenous fluids, were associated with lower risk-adjusted in-hospital mortality.... Read More

This nICP estimation algorithm, based on arterial blood pressure (ABP) and bedside transcranial Doppler (TCD) cerebral blood flow velocity (CBFV) waveform measurements, performs in a manner comparable to invasive intracranial... Read More

Two simple and available upon admission clinical predictors of group A streptococcus (GAS) documentation identified among a large cohort of surgically proven necrotizing soft tissue infections (NSTIs). The results show that... Read More

This book introduces the latest advances relating to the pathophysiology, biophysics, monitoring and treatment of traumatic brain injury, hydrocephalus, and stroke presented at the 16th International Conference on Intracranial... Read More

Sometimes our body’s reaction to infection can result in damage to internal tissues and organs. Such a condition is referred to as sepsis. Some of the symptoms of sepsis are high fever, increased heart and breathing... Read More

Statistically significant results in anesthesia and critical care randomized controlled trials are often fragile, and study conclusions are frequently affected by spin. Routine calculation of the Fragility Index in medical... Read More

Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population. Several clinical disorders can initiate ARDS,... Read More

ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical... Read More