Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Compared with standard calorie and protein targets, early calorie and protein restriction did not decrease mortality but was associated with faster recovery and fewer complications. Of 3,044 patients randomly assigned... read more

6 Days Higher-Dose Ivermectin vs. Placebo on Time to Sustained Recovery in COVID-19 Outpatients

6 Days Higher-Dose Ivermectin vs. Placebo on Time to Sustained Recovery in COVID-19 Outpatients

Among a largely vaccinated outpatient population with mild to moderate COVID-19, treatment with ivermectin, with a targeted maximum dose of 600 μg/kg daily for 6 days, compared with placebo was not shown to improve time... read more

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

This analysis of a large randomized trial involving people who are at high risk of experiencing severe outcomes from COVID-19 and who had been vaccinated against SARS-CoV-2 infection found that adding molnupiravir to usual... read more

House Officer’s Guide to ICU Care

House Officer’s Guide to ICU Care

Your Must-Have Guide for Navigating the ICU The House Officer's Guide to ICU Care is an eminently practical handbook for junior house officers, medical students, PAs, and nurses that offers nuts-and-bolts guidelines for optimal... read more

Sedation Management Evolution in the ICU

Sedation Management Evolution in the ICU

This paper provided an overview of how ICU sedation practices have evolved over the last 20 years. Contemporary ICU sedation practices include light levels of sedation, SAT, and use of non-benzodiazepines. The current... read more

Mental Health Morbidity Among Caregivers

Mental Health Morbidity Among Caregivers

While much of the research on post-ICU mental health morbidity has focused upon the survivors themselves, emerging data shows that caregivers of ICU patients are similarly impacted. The collective sequelae experienced... read more

Multiple Organ Dysfunction in Older Major Trauma Critical Care Patients

Multiple Organ Dysfunction in Older Major Trauma Critical Care Patients

Frailty rather than chronological age appears to drive multiple organ dysfunction syndrome (MODS) development, recovery, and outcome in older cohorts. Early identification of frailty after trauma may help to predict MODS... read more

Subclavian vs. Femoral Arterial Cannulations During ECMO

Subclavian vs. Femoral Arterial Cannulations During ECMO

During peripheral extracorporeal veno-arterial membrane oxygenation (VA-ECMO) support, subclavian arterial cannulation provides, in comparison to femoral arterial cannulation, an anterograde flow which may prevent from left... read more

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

This book is a practical manual for anti-COVID-19. It is not only with the reference to the result of modern medical science, patients' situation, but also take the deployment of medical resources into consideration. Content... read more

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients

Among hospitalised COVID-19 patients needing oxygen therapy, high dose of dexamethasone reduced clinical worsening within 11 days after randomisation as compared with low dose of dexamethasone. Further studies are necessary... read more

High-Flow Oxygen Therapy vs. Conventional Oxygen Therapy on Invasive Mechanical Ventilation in COVID-19 Patients

High-Flow Oxygen Therapy vs. Conventional Oxygen Therapy on Invasive Mechanical Ventilation in COVID-19 Patients

Among patients with severe COVID-19, use of high-flow oxygen through a nasal cannula significantly decreased need for mechanical ventilation support and time to clinical recovery compared with conventional low-flow oxygen... read more

Recovery, Rehabilitation and Follow-up Services After Critical Illness

Recovery, Rehabilitation and Follow-up Services After Critical Illness

Overall, these data demonstrate a proliferation of recovery, follow-up and rehabilitation services for critically ill adults in the past decade across the UK, although service gaps remain suggesting further work is required... read more

Higher CRP Rise Not Related To Cytokine Response

Higher CRP Rise Not Related To Cytokine Response

The higher C-reactive protein (CRP) rise with late parenteral nutrition (PN), explained by the early macronutrient deficits, did not relate to cytokine responses and thus did not reflect more systemic inflammation. Instead... read more

Improving Critical Care Survivorship: A Guide to Prevention, Recovery, and Reintegration

Improving Critical Care Survivorship: A Guide to Prevention, Recovery, and Reintegration

This book, just published, provides a comprehensive overview of improving critical care survivorship. Comprised of four sections, the text presents interventions that can be used to improve patient outcomes and reduce the... read more