Patients recovering from an episode of hypoxemic acute respiratory failure (hARF) may benefit from a weaning strategy based on early extubation followed by immediate noninvasive ventilation (NIV) application. Compared to... read more

The second edition of this educational book provides an updated resource on how best to discuss and manage acute and chronic presentations of renal diseases. All chapters have been reviewed and updated to reflect changes... read more

Coronavirus disease 2019 (COVID-19) pneumonia is associated with hypoxemic respiratory failure, ranging from mild to severe. Due to the worldwide shortage of intensive care unit beds, a relatively high number of patients... read more

Compared to acute respiratory distress syndrome (ARDS) patients without COVID-19, patients with COVID-19 had similar lung mechanics, but higher extravascular lung water index (EVLWi) and pulmonary vascular permeability index... read more

Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more

This workbook focuses on renal replacement therapy in ICU. The incidence of acute kidney injury in critically ill patients is increasing steeply. Acute kidney injury in this setting is associated with high morbidity and mortality.... read more

Careful descriptions of the clinical features of acute disease in patients infected with the novel coronavirus SARS-CoV-2 had begun to emerge before WHO declared the outbreak of COVID-19 a public health emergency of international... read more

In critically ill survivors, achieving higher levels of mobilization, but not increasing the number of active mobilization sessions, improved health status 6 months after ICU admission. The dosage of mobilization in ICU was... read more

Since the lockdown because of the pandemic, family members have been prohibited from visiting their loved ones in hospital. While it is clearly complicated to implement protocols for the admission of family members, we believe... read more

This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings... read more

Early prehospital and in-hospital S100B levels  0.10 μg/L was 100% (95%CI: 89.1;100.0) in prehospital samples and 100% (95% CI 89.1;100.0) in in-hospital samples. The specificity was 15.4% (95%CI: 12.4;18.7) in prehospital... read more

Left ventricular function measured by LVFS is positively correlated with higher probability of rates of return of spontaneous circulation (ROSC) and may be associated with higher chances of survival in patients with PEA arrest.... read more

Increased recognition of the overlap between critical care and renal medicine, and recent advances in the understanding of acute renal failure (ARF) and the application of renal replacement therapies (RRTs), have brought... read more

Inhaled nitric oxide (iNO) is used for refractory hypoxemia in acute respiratory distress syndrome (ARDS) via vasodilation of pulmonary arterioles to ventilated alveoli, particularly in pediatrics. However, iNO has not affected... read more

The abnormal interaction between the right ventricle (RV) and pulmonary vasculature in various disease states is associated with adverse clinical outcomes. Impaired RV physiology in acute respiratory distress syndrome (ARDS)... read more

In hospitalized patients with coronavirus disease 2019, a very limited echocardiographic examination is sufficient for outcome prediction. The addition of echocardiography in patients with high-risk MEWS decreases the rate... read more

Cardiovascular collapse is a common complication during tracheal intubation of critically ill adults. Whether administration of an intravenous fluid bolus prevents cardiovascular collapse during tracheal intubation remains... read more

This intervention study shows that a 2-h education in situation awareness improved parts of team performance in an acute care situation. Team leadership and task management improved in the intervention group, which may indicate... read more