Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU

Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU

In critically ill patients who were not receiving early parenteral nutrition, tight glucose control did not affect the length of time that ICU care was needed or mortality. Of 9,230 patients who underwent randomization,... read more

Significant Persistent Pain Symptoms After Critical Care Illness

Significant Persistent Pain Symptoms After Critical Care Illness

Persistent pain could be a common health problem after critical illness care. Our data also suggest that there is a lack of specific follow-up after ICU discharge. Given the major consequences on patient quality of life,... read more

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Compared with standard calorie and protein targets, early calorie and protein restriction did not decrease mortality but was associated with faster recovery and fewer complications. Of 3,044 patients randomly assigned... read more

Higher Protein Dosing in Critically Ill Patients with High Nutritional Risk

Higher Protein Dosing in Critically Ill Patients with High Nutritional Risk

Delivery of higher doses of protein to mechanically ventilated critically ill patients did not improve the time-to-discharge-alive from hospital and might have worsened outcomes for patients with acute kidney injury (AKI)... read more

Medical Nutrition Therapy and Clinical Outcomes in Critically Ill Adults

Medical Nutrition Therapy and Clinical Outcomes in Critically Ill Adults

Calorie intake was mainly provided according to the targets recommended by the active ESPEN guideline, but protein intake was lower. In patients staying in ICU ≥ 5 days, early moderate daily calorie and protein intakes... read more

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

COVID-19 considerably impacted swallowing function in the current study. Although many patients recovered within an acceptable timeframe, some experienced persistent severe dysphagia and a protracted recovery with dependence... read more

Impact of Tight Glucose Control on Circulating 3-hydroxybutyrate in Critically Ill Patients

Impact of Tight Glucose Control on Circulating 3-hydroxybutyrate in Critically Ill Patients

Tight versus liberal glucose control in the context of early parenteral nutrition did not affect 3-hydroxybutyrate concentrations in critically ill patients. Hence, the protective effects of tight glucose control in this... read more

Workbook on Renal Replacement Therapy in ICU (ISCCM)

Workbook on Renal Replacement Therapy in ICU (ISCCM)

This workbook focuses on renal replacement therapy in ICU. The incidence of acute kidney injury in critically ill patients is increasing steeply. Acute kidney injury in this setting is associated with high morbidity and mortality.... read more

Low Technology, Mild Controlled Hypothermia for Necrotizing Enterocolitis Treatment

Low Technology, Mild Controlled Hypothermia for Necrotizing Enterocolitis Treatment

Low technology, mild controlled hypothermia was feasible, not related to adverse effects, and effective treatment for NEC Modified Bell's Stage II/III. It avoided surgery, bowel perforation, and extensive intestinal resection;... read more

Effect of Infusion Set Replacement Intervals on Catheter-related Bloodstream Infections

Effect of Infusion Set Replacement Intervals on Catheter-related Bloodstream Infections

The optimal duration of infusion set use to prevent life-threatening catheter-related bloodstream infection (CRBSI) is unclear. We aimed to compare the effectiveness and costs of 7-day (intervention) versus 4-day (control)... read more

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

Non-resuscitation fluid in excess of hydration requirements is associated with increased mortality in critically ill children. Excess maintenance fluid is a modifiable contributor to this fluid volume. Strategies to reduce... read more

Overcoming Enteral Nutrition Delivery Challenges in Critical Care

Overcoming Enteral Nutrition Delivery Challenges in Critical Care

It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized... read more

Nutritional Risk Screening and Body Composition in COVID-19 Patients

Nutritional Risk Screening and Body Composition in COVID-19 Patients

Present findings confirm the clinical utility of NRS-2002 to assess nutritional risk in patients with COVID-19 at hospital admission and in predicting LOS, and that bioimpedance does not seem to add further predictive value.... read more

Effect of Early Activity Combined with Early Nutrition on Acquired Weakness in ICU Patients

Effect of Early Activity Combined with Early Nutrition on Acquired Weakness in ICU Patients

This trial has the potential to identify a novel strategy for preventing or managing ICU-AW. The findings may increase the clinical knowledge about nutrition and mobilization interventions for people with ICU-AW, and contribute... read more