Hypoxemia and tachypnea should not be the sole indications for intubation, but rather a complete clinical assessment including work of breathing, mental status and increasing PaCO2 and/or acidosis. Based on experience in... Read More

Non-invasive ventilation (NIV) is applied worldwide to patients with hypoxemic respiratory failure. It is often applied as an attempt to avoid invasive mechanical ventilation. However, the application of NIV is often ad hoc... Read More

Lung-protective ventilation for acute respiratory distress syndrome (ARDS) aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of mechanical ventilation. This study indicates... Read More

The extracorporeal membrane oxygenation(ECMO)-associated coagulopathy is a multifactorial and quickly developing syndrome. It is characterized by individual changes of coagulation parameters and platelets and is aggravated... Read More

Emory University Department of Emergency Medicine and Grady Memorial Hospital will take part in a U.S. Department of Defense-funded clinical trial to compare different ways to help people with traumatic injuries breathe.... Read More

Clinically significant pleural effusion (PLEFF)—defined by a depth greater than or equal to 2 cm in a drainable location on thoracic ultrasound together with a potential adverse effect on patient progress—was detected... Read More

Although the primary outcome was not statistically robust to conservative assumptions about missing data, the trial provides modest evidence that conservative management of primary spontaneous pneumothorax was noninferior... Read More

This study suggests that levosimendan might be associated with a beneficial effect on venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in ICU patients. The difference in mortality among propensity-matched... Read More

Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Inability to rapidly restore microcirculation during the first 24 hours,... Read More

Cerebral auto-regulation was altered in half of the patients with sepsis and was associated with the development of SABD. These findings support the concept that cerebral hypoxia could contribute to the development of sepsis-associated... Read More

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... Read More

Implementation of apneic oxygenation in PICU was feasible, and was associated with significant reduction in moderate and severe oxygen desaturation. Use of apneic oxygenation should be considered when intubating critically... Read More

Although there are no specific data regarding the effect of respiratory management on stroke patients’ outcomes, specific ventilator strategies in this population could potentially improve neurologic outcome and prevent... Read More

The purpose of this study was to evaluate survival to hospital discharge for patients on venovenous extracorporeal membrane oxygenation (VV ECMO) when stratified by age. We performed a retrospective study at single, academic,... Read More

The Food and Drug Administration on Monday approved a once-daily pill for sickle cell disease that works in an entirely new way — by boosting hemoglobin, the oxygen-carrying molecule found in red blood cells. The novel... Read More