Recently, novel coronavirus 2019 (nCOV-19) is spreading all around the world causing severe acute respiratory syndrome (SARS-CoV-2) requiring mechanical ventilation in about 5% of infected people. Prone position ventilation... read more

This is the first report on a first-in-human clinical trial of a novel Ad5 vectored COVID-19 vaccine. The Ad5 vectored COVID-19 vaccine was tolerated in healthy adults in all three dose groups. The most common adverse reactions... read more

This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more

Initial reports have indicated a higher incidence of venous thromboembolism (VTE) among patients with coronavirus disease 2019 (COVID-19) compared to other critical illnesses. Helms et al. found pulmonary embolisms in 25%... read more

The authors concluded that RAAS inhibitors do not increase the risk of COVID-19 requiring admission to the hospital, including fatal cases and those admitted to intensive care units (ICUs), and should not be discontinued... read more

The treatment of patients with coronavirus disease (COVID-19) needs to take into consideration not only the disease process but also the availability of medical resources and the risks of transmission to healthcare providers.... read more

This book is a practical and easily understandable guide for mechanical ventilation. With a focus on the basics, this text begins with a detailed account of the mechanisms of spontaneous breathing as a reference point to... read more

Gilead’s first Randomized Controlled Trial on remdesivir was just published, and it’s very interesting. This is a trial designed, monitored, and written by Gilead. In some ways, the design of the trial and its... read more

The healthcare burden of the coronavirus disease 2019 (COVID-19) pandemic extends beyond patients who test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a retrospective cohort study... read more

Despite decades of experience with endotracheal intubation, we continue to find approaches to improving the process of how we intubate. In today’s post we are not only going to talk about how to avoid post intubation... read more

H.R. 6910, critical bipartisan legislation to ensure every emergency physician has medical staff due process rights was recently introduced by emergency physician and member of Congress, Rep. Raul Ruiz, MD (D-CA), and Rep.... read more

Bedside Procedures for the Intensivist delivers practical tips and clear, step-by-step instruction on the most common procedures in the ICU. The convenient and portable handbook focuses on ultrasound-guided techniques, including... read more

Based on our preliminary case series, awake open surgery has resulted feasible and safe. This approach has allowed to perform undelayable major abdominal surgeries on fragile patients when intensive care beds were not available.... read more

Unfractionated heparin (UFH) binds to anti-thrombin III (AT-III), which enhances antithrombin’s inhibition of several coagulation factors – especially factor Xa and factor IIa (thrombin). Low Molecular-Weight Heparin... read more

During the coronavirus disease (COVID-19) global pandemic, urgent strategies to alleviate shortages are required. Evaluation of the feasibility, practicality, and value of drug conservation strategies and therapeutic alternatives... read more

This study examined the long-term health-related quality of life in adult patients treated with venovenous extracorporeal membrane oxygenation (V-V ECMO) for severe acute respiratory failure in Ireland. A retrospective, cross-sectional... read more

This volume provides a comprehensive overview of hematologic issues that clinicians regularly encounter in the critical care environment. The text features hematologic scenarios that affect the adult ICU patient, outlines... read more

There are notable differences in baseline predisposition, host responses, and clinical outcomes by site of infection in surgical sepsis. While previous studies have focused on differences in hospital mortality, this study... read more